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Western Blot (WB)

Rabbit anti-Mouse, Rat Dopamine D2 Receptor Polyclonal Antibody | anti-Drd2 antibody

Dopamine D2 Receptor Antibody

Reactivity
Mouse, Rat
Applications
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Synonyms
Dopamine D2 Receptor; Polyclonal Antibody; Dopamine D2 Receptor Antibody; D(2) dopamine receptor; D2 dopamine receptor; D2DR; D2R; Dopamine D2 receptor; DRD2 antibody; anti-Drd2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
0.55ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
415
Applicable Applications for anti-Drd2 antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ELISA: 1:50,000
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Immunoprecipitation: 1:200
Western Blot: 1:1,000-1:1,5000
Immunogen
Synthetic peptide taken within amino acid region 150-200 on rat Dopamine Receptor D2 protein.
Immunoglobulin
IgG
Molecular Function
Dopamine Binding; Potassium Channel Regulator activity; Identical Protein binding
Structure
Forms homo- and heterooligomers with DRD4. The interaction with DRD4 may modulate agonist-induced downstream signaling. Interacts with GPRASP1, PPP1R9B and CLIC6 (By similarity). Interacts with CADPS and CADPS2. Interacts with ARRB2 (By similarity). Interacts with KCNA2 (By similarity). Interacts with GNAI1 (PubMed:17264214). Interacts with GNAI2 isoform sGi2, the interaction allows the creation of an intracellular pool of DRD2 that can be released to cell surface upon agonist stimulation. Interacts with HTR2A.
Subcellular Location
Cell membrane; Multi-pass membrane protein
Preparation and Storage
-20 degree C for long term storage

Western Blot (WB)

Western Blot (WB)

Western Blot (WB)

Western Blot (WB)
Related Product Information for anti-Drd2 antibody
Affinity Purified Dopamine Receptor subtype D2 Antibody
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
20,091 Da
NCBI Official Full Name
dopamine receptor subtype D2
NCBI Official Synonym Full Names
dopamine receptor D2
NCBI Official Symbol
Drd2
NCBI Protein Information
D(2) dopamine receptor
UniProt Protein Name
D(2) dopamine receptor
Protein Family
UniProt Gene Name
DRD2
UniProt Entry Name
Q6LDH7_HUMAN

NCBI Description

mediates G-protein coupled signaling; may be involved in movement disorders, schizophrenia, and drug addiction [RGD, Feb 2006]

Research Articles on Drd2

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Product Notes

The Drd2 drd2 (Catalog #AAA540357) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Dopamine D2 Receptor Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Dopamine D2 Receptor can be used in a range of immunoassay formats including, but not limited to, Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:50,000 Immunocytochemistry: 1:200 Immunofluorescence: 1:200 Immunohistochemistry: 1:200 Immunoprecipitation: 1:200 Western Blot: 1:1,000-1:1,5000. Researchers should empirically determine the suitability of the Drd2 drd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Dopamine D2 Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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