Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DOCK11 Polyclonal Antibody at dilution of 1:35(×200))
Rabbit anti-Human, Mouse DOCK11 Polyclonal Antibody | anti-DOCK11 antibody
DOCK11 Polyclonal Antibody
Gene Names
DOCK11; ACG; ZIZ2; bB128O4.1
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
DOCK11; Polyclonal Antibody; DOCK11 Polyclonal Antibody; ACG; Activated Cdc42-associated guanine nucleotide exchange factor; Dedicator of cytokinesis protein 11; DOC11; Dock11; ZIZ2; Zizimin-2; anti-DOCK11 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
1.32mg/mL (varies by lot)
Sequence Length
2073
Applicable Applications for anti-DOCK11 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:20-1:100
ELISA: 1:5000-1:10000
ELISA: 1:5000-1:10000
Immunogen
Synthetic peptide of human DOCK11
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DOCK11 Polyclonal Antibody at dilution of 1:35(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DOCK11 Polyclonal Antibody at dilution of 1:35(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using DOCK11 Polyclonal Antibody at dilution of 1:35(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using DOCK11 Polyclonal Antibody at dilution of 1:35(×200))
Related Product Information for anti-DOCK11 antibody
Small GTPases of the Rho family, Rho, Rac, and Cdc42, are critical regulators of the actin cytoskeleton and many other cellular processes. Rho GTPases are activated by Dbl-homology (DH)-domain-containing guanine nucleotide exchange factors (GEFs). DOCK 11 (dedicator of cytokinesis 11), also known as ACG or ZIZ2 (zizimin2), is a 2073 amino acid protein belonging to the DOCK family of cytokinesis-regulating proteins that is mainly expressed in peripheral blood leukocytes. DOCK 11 functions as a GEF that binds and activates Cdc42 by exchanging bound GDP for free GTP. Cdc42 mediates cell polarity, gene expression, cell cycle progression and cell-cell contacts. Similar to other DOCK family members, DOCK 11 contains a PH domain and two internal DOCK homology regions designated DHR1 and DHR2.
Product Categories/Family for anti-DOCK11 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
dedicator of cytokinesis protein 11
NCBI Official Synonym Full Names
dedicator of cytokinesis 11
NCBI Official Symbol
DOCK11
NCBI Official Synonym Symbols
ACG; ZIZ2; bB128O4.1
NCBI Protein Information
dedicator of cytokinesis protein 11
UniProt Protein Name
Dedicator of cytokinesis protein 11
Protein Family
UniProt Gene Name
DOCK11
UniProt Synonym Gene Names
ZIZ2; ACG
UniProt Entry Name
DOC11_HUMAN
Uniprot Description
DOCK11: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Belongs to the DOCK family.
Protein type: GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: Xq24
Cellular Component: cytosol
Molecular Function: Rho guanyl-nucleotide exchange factor activity; Rho GTPase binding
Biological Process: small GTPase mediated signal transduction; blood coagulation
Similar Products
Product Notes
The DOCK11 dock11 (Catalog #AAA2559780) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DOCK11 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DOCK11 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:20-1:100 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the DOCK11 dock11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DOCK11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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