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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver using MBS768692 (DNAJC15 antibody) at dilution of 1:100)

Rabbit DNAJC15 Polyclonal Antibody | anti-DNAJC15 antibody

DNAJC15 Rabbit Polyclonal

Gene Names
DNAJC15; MCJ; HSD18; DNAJD1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
DNAJC15; Polyclonal Antibody; DNAJC15 Rabbit Polyclonal; anti-DNAJC15 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
150
Applicable Applications for anti-DNAJC15 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
DnaJ (Hsp40) homolog, subfamily C, member 15
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver using MBS768692 (DNAJC15 antibody) at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver using MBS768692 (DNAJC15 antibody) at dilution of 1:100)

Western Blot (WB)

(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS768692 (DNAJC15 antibody) at dilution of 1:1000)

Western Blot (WB) (mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS768692 (DNAJC15 antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,383 Da
NCBI Official Full Name
dnaJ homolog subfamily C member 15
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member C15
NCBI Official Symbol
DNAJC15
NCBI Official Synonym Symbols
MCJ; HSD18; DNAJD1
NCBI Protein Information
dnaJ homolog subfamily C member 15
UniProt Protein Name
DnaJ homolog subfamily C member 15
Protein Family
UniProt Gene Name
DNAJC15
UniProt Synonym Gene Names
DNAJD1; MCJ
UniProt Entry Name
DJC15_HUMAN

Uniprot Description

DNAJC15: Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP. Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9. Interacts with the TIM23 complex. Directly interacts with PAM16/MAGMAS; this interaction counteracts DNAJC15-dependent stimulation of HSPA9 ATPase activity. Associates with complex I of the mitochondrial electron transfer chain; this interaction may interfere with the formation of supercomplexes that facilitate the transfer of electrons between complexes

Protein type: Chaperone; Membrane protein, integral; Mitochondrial; Cell adhesion

Chromosomal Location of Human Ortholog: 13q14.1

Cellular Component: integral to membrane; mitochondrial inner membrane

Molecular Function: protein binding

Biological Process: cellular response to starvation; negative regulation of protein complex assembly; protein transport; regulation of lipid metabolic process

Research Articles on DNAJC15

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Product Notes

The DNAJC15 dnajc15 (Catalog #AAA768692) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DNAJC15 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DNAJC15 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the DNAJC15 dnajc15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNAJC15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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