Testing Data
(Sample (30 ug of whole cell lysate)A: Molt-4 7.5 % SDS PAGEPrimary antibody diluted at 1: 1000)
Rabbit anti-Human DNAI2 Polyclonal Antibody | anti-DNAI2 antibody
DNAI2 antibody
Testing Data
(Sample (30 ug of whole cell lysate)A: Molt-4 7.5 % SDS PAGEPrimary antibody diluted at 1: 1000)
Testing Data
(Sample (30 ug of whole cell lysate)A: Molt-4 7.5 % SDS PAGEPrimary antibody diluted at 1: 1000)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella. Mutations in this gene are associated with primary ciliary dyskinesia type 9. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2010]
Uniprot Description
DNAI2: Part of the dynein complex of respiratory cilia. Defects in DNAI2 are the cause of primary ciliary dyskinesia type 9 (CILD9). CILD is an autosomal recessive disorder characterized by axonemal abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit situs inversus, due to dysfunction of monocilia at the embryonic node and randomization of left-right body asymmetry. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Belongs to the dynein intermediate chain family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motor; Microtubule-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17q25
Cellular Component: microtubule; axonemal dynein complex; axoneme
Molecular Function: protein binding; microtubule motor activity
Biological Process: metabolic process; cilium biogenesis
Disease: Ciliary Dyskinesia, Primary, 9
Research Articles on DNAI2
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Product Notes
The DNAI2 dnai2 (Catalog #AAA9405026) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DNAI2 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DNAI2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500-1:3000. Researchers should empirically determine the suitability of the DNAI2 dnai2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNAI2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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