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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer tissue using DLL4 Polyclonal Antibody at dilution 1:50)

Rabbit DLL4 Polyclonal Antibody | anti-DLL4 antibody

DLL4 Polyclonal Antibody

Gene Names
DLL4; hdelta2
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
DLL4; Polyclonal Antibody; DLL4 Polyclonal Antibody; hdelta2; anti-DLL4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.4mg/mL (varies by lot)
Sequence Length
685
Applicable Applications for anti-DLL4 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:100-1:300
Immunogen
Recombinant protein of human DLL4
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human breast cancer tissue using DLL4 Polyclonal Antibody at dilution 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer tissue using DLL4 Polyclonal Antibody at dilution 1:50)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DLL4 Polyclonal Antibody at dilution 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DLL4 Polyclonal Antibody at dilution 1:50)
Related Product Information for anti-DLL4 antibody
This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.
Product Categories/Family for anti-DLL4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74,605 Da
NCBI Official Full Name
delta-like protein 4
NCBI Official Synonym Full Names
delta-like 4 (Drosophila)
NCBI Official Symbol
DLL4
NCBI Official Synonym Symbols
hdelta2
NCBI Protein Information
delta-like protein 4; delta 4; delta ligand 4; delta-like 4 homolog; delta-like 4 protein; delta4; drosophila Delta homolog 4; notch ligand DLL4; notch ligand delta-2
UniProt Protein Name
Delta-like protein 4
Protein Family
UniProt Gene Name
DLL4
UniProt Synonym Gene Names
Delta4
UniProt Entry Name
DLL4_HUMAN

NCBI Description

This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008]

Uniprot Description

DLL4: Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4. Binds to Notch-1 and Notch-4. Expressed in vascular endothelium.

Protein type: Cell development/differentiation; Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: plasma membrane; integral to membrane

Molecular Function: calcium ion binding; Notch binding

Biological Process: patterning of blood vessels; negative regulation of cell proliferation; Notch signaling pathway; regulation of neurogenesis; visual perception; blood circulation; Notch receptor processing; blood vessel remodeling; angiogenesis; negative regulation of transcription from RNA polymerase II promoter; signal transduction

Research Articles on DLL4

Similar Products

Product Notes

The DLL4 dll4 (Catalog #AAA2530117) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DLL4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DLL4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:100-1:300. Researchers should empirically determine the suitability of the DLL4 dll4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DLL4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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