Rabbit anti-Human DISP2 Polyclonal Antibody | anti-DISP2 antibody

Rabbit Polyclonal to Human DISP2

Cat. Num. AAA246905

• Gene Names: DISP2; DISPB; HsT16908
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: DISP2; Polyclonal Antibody; Rabbit Polyclonal to Human DISP2; Anti-DISP2 Antibody (N-Terminus) IHC-plus; DISPB; Protein dispatched homolog 2; Dispatched B; HsT16908; KIAA1742; Human DISP2; anti-DISP2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.02% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 1401

• Applicable Applications for anti-DISP2 antibody: Immunohistochemistry (IHC - Paraffin)
• Application Notes: IHC-P (5 ug/ml)
• Target Species: Human
• Immunogen Description: An 18 amino acid peptide near the amino terminus of human DISP2.
• Immunogen Type: Synthetic peptide
• Immunogen: DISP2 antibody was raised against an 18 amino acid peptide near the amino terminus of human DISP2.
• Antigen Modification: N-Terminus
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-DISP2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 25121980
• NCBI GeneID: 85455
• NCBI Accession #: NP_277045.1
• NCBI GenBank Nucleotide #: NM_033510.1
• UniProt Accession #: A7MBM2; Q6AHW3; Q9C0C1
• Molecular Weight: 152,003 Da
• NCBI Official Full Name: protein dispatched homolog 2
• NCBI Official Synonym Full Names: dispatched homolog 2 (Drosophila)
• NCBI Official Symbol: DISP2
• NCBI Official Synonym Symbols: DISPB; HsT16908
• NCBI Protein Information: protein dispatched homolog 2; dispatched B
• UniProt Protein Name: Protein dispatched homolog 2
• Protein Family: Protein dispatched
• UniProt Gene Name: DISP2
• UniProt Synonym Gene Names: DISPB; KIAA1742
• UniProt Entry Name: DISP2_HUMAN

NCBI Description

The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched. [provided by RefSeq, Jul 2008]

Uniprot Description

DISP2: The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: integral to membrane; plasma membrane

Biological Process: smoothened signaling pathway