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Western Blot (WB) (All lanes: Disintegrin and metalloproteinase domain-containing protein 9 antibody at 2ug/mlLane 1:mouse liver tissueLane 2:mouse heart tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 91,73 kDaObserved band size: 91 kDa)

Rabbit anti-Human, Mouse Disintegrin and metalloproteinase domain-containing protein 9 Polyclonal Antibody | anti-ADAM9 antibody

Rabbit anti-human Disintegrin and metalloproteinase domain-containing protein 9 polyclonal Antibody(ADAM9)

Gene Names
ADAM9; MCMP; MDC9; CORD9; Mltng
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
Disintegrin and metalloproteinase domain-containing protein 9; Polyclonal Antibody; Rabbit anti-human Disintegrin and metalloproteinase domain-containing protein 9 polyclonal Antibody(ADAM9); ADAM 9; Cellular disintegrin-related protein; Meltrin-gamma; Metalloprotease/disintegrin/cysteine-rich protein 9; Myeloma cell metalloproteinase; ADAM9; KIAA0021; MCMP; MDC9; MLTNG; anti-ADAM9 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
819
Applicable Applications for anti-ADAM9 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: WB:1:500-2000
IHC:1:20-1:200
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Disintegrin and metalloproteinase domain-containing protein 9 protein(475-685aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23290 / sc-50332
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(All lanes: Disintegrin and metalloproteinase domain-containing protein 9 antibody at 2ug/mlLane 1:mouse liver tissueLane 2:mouse heart tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 91,73 kDaObserved band size: 91 kDa)

Western Blot (WB) (All lanes: Disintegrin and metalloproteinase domain-containing protein 9 antibody at 2ug/mlLane 1:mouse liver tissueLane 2:mouse heart tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 91,73 kDaObserved band size: 91 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver cancer using MBS1495748 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver cancer using MBS1495748 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human placenta using MBS1495748 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human placenta using MBS1495748 at dilution 1:100)
Related Product Information for anti-ADAM9 antibody
Probable zinc protease. May mediate cell-cell or cell-matrix interactions. Isoform 2 displays alpha-secretase activity for APP.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
72,359 Da
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 9
NCBI Official Synonym Full Names
ADAM metallopeptidase domain 9
NCBI Official Symbol
ADAM9
NCBI Official Synonym Symbols
MCMP; MDC9; CORD9; Mltng
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 9
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 9
UniProt Gene Name
ADAM9
UniProt Synonym Gene Names
KIAA0021; MCMP; MDC9; MLTNG; ADAM 9
UniProt Entry Name
ADAM9_HUMAN

NCBI Description

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]

Uniprot Description

ADAM9: Probable zinc protease. May mediate cell-cell or cell- matrix interactions. Isoform 2 displays alpha-secretase activity for APP. Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; EC 3.4.24.-; Protease

Chromosomal Location of Human Ortholog: 8p11.22

Cellular Component: cell surface; cytoplasm; extracellular space; focal adhesion; integral to membrane

Molecular Function: collagen binding; integrin binding; laminin binding; metalloendopeptidase activity; metallopeptidase activity; protein binding; protein kinase C binding; SH3 domain binding; zinc ion binding

Biological Process: activation of MAPKK activity; cell adhesion; cell adhesion mediated by integrin; cell-cell adhesion mediated by integrin; cell-matrix adhesion; collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; integrin-mediated signaling pathway; keratinocyte differentiation; membrane protein ectodomain proteolysis; monocyte activation; PMA-inducible membrane protein ectodomain proteolysis; positive regulation of cell adhesion mediated by integrin; positive regulation of keratinocyte migration; positive regulation of membrane protein ectodomain proteolysis; positive regulation of protein secretion; response to calcium ion; response to glucocorticoid stimulus; response to hydrogen peroxide; response to manganese ion; transforming growth factor beta receptor signaling pathway

Disease: Cone-rod Dystrophy 9

Research Articles on ADAM9

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Product Notes

The ADAM9 adam9 (Catalog #AAA1495748) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Disintegrin and metalloproteinase domain-containing protein 9 polyclonal Antibody(ADAM9) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Disintegrin and metalloproteinase domain-containing protein 9 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Recommended dilution: WB:1:500-2000 IHC:1:20-1:200. Researchers should empirically determine the suitability of the ADAM9 adam9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Disintegrin and metalloproteinase domain-containing protein 9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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