Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using DHX8 antibody.)
Rabbit anti-Human DHX8 Polyclonal Antibody | anti-DHX8 antibody
DHX8 Polyclonal Antibody
Gene Names
DHX8; DDX8; Dhr2; HRH1; PRP22; PRPF22
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purification
Synonyms
DHX8; Polyclonal Antibody; DHX8 Polyclonal Antibody; ATP dependent RNA helicase DHX8; ATP-dependent RNA helicase dhx8; DDX 8; DDX8; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 (RNA helicase); DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8; DEAD/H box 8; DEAD/H box polypeptide 8; DEAH (Asp Glu Ala His) box polypeptide 8; DEAH box polypeptide 8; DEAH box protein 8; DHX 8; dhx8; HRH 1; HRH1; PRP 22; PRP22; S. cerevisiae; homolog of; PRPF 22; PRPF22; RNA helicase HRH 1; RNA helicase HRH1; anti-DHX8 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration
1 mg/mL (varies by lot)
Sequence Length
1,220
Applicable Applications for anti-DHX8 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human DHX8
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using DHX8 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using DHX8 antibody.)
Related Product Information for anti-DHX8 antibody
This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-DHX8 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated: 139kDa
Observed: 150kDa
Observed: 150kDa
NCBI Official Full Name
ATP-dependent RNA helicase DHX8 isoform 2
NCBI Official Synonym Full Names
DEAH-box helicase 8
NCBI Official Symbol
DHX8
NCBI Official Synonym Symbols
DDX8; Dhr2; HRH1; PRP22; PRPF22
NCBI Protein Information
ATP-dependent RNA helicase DHX8
UniProt Protein Name
ATP-dependent RNA helicase DHX8
Protein Family
UniProt Gene Name
DHX8
UniProt Synonym Gene Names
DDX8
NCBI Description
This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Uniprot Description
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28076346). Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome (PubMed:8608946).
Research Articles on DHX8
Similar Products
Product Notes
The DHX8 dhx8 (Catalog #AAA2555459) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DHX8 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DHX8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the DHX8 dhx8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DHX8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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