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Western Blot (WB) (Western blotAll lanes: DHTKD1 antibody at 1.82 ug/mlLane 1: Mouse heart tissueLane 2: Mouse liver tissueLane 3: Mouse kidney tissueLane 4: A431 whole cell lysateLane 5: MCF7 whole cell lysateLane 6: HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 103 kDaObserved band size: 103 kDa)

Rabbit anti-Human, Mouse DHTKD1 Polyclonal Antibody | anti-DHTKD1 antibody

DHTKD1 Antibody

Gene Names
DHTKD1; CMT2Q; AMOXAD
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
DHTKD1; Polyclonal Antibody; DHTKD1 Antibody; Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1; mitochondrial; Dehydrogenase E1 and transketolase domain-containing protein 1; KIAA1630; anti-DHTKD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
919
Applicable Applications for anti-DHTKD1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial protein (N-280AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: DHTKD1 antibody at 1.82 ug/mlLane 1: Mouse heart tissueLane 2: Mouse liver tissueLane 3: Mouse kidney tissueLane 4: A431 whole cell lysateLane 5: MCF7 whole cell lysateLane 6: HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 103 kDaObserved band size: 103 kDa)

Western Blot (WB) (Western blotAll lanes: DHTKD1 antibody at 1.82 ug/mlLane 1: Mouse heart tissueLane 2: Mouse liver tissueLane 3: Mouse kidney tissueLane 4: A431 whole cell lysateLane 5: MCF7 whole cell lysateLane 6: HepG-2 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 103 kDaObserved band size: 103 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7044987 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7044987 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain tissue using MBS7044987 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain tissue using MBS7044987 at dilution of 1:100)
Related Product Information for anti-DHTKD1 antibody
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
103,077 Da
NCBI Official Full Name
probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
NCBI Official Synonym Full Names
dehydrogenase E1 and transketolase domain containing 1
NCBI Official Symbol
DHTKD1
NCBI Official Synonym Symbols
CMT2Q; AMOXAD
NCBI Protein Information
probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
UniProt Protein Name
Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
UniProt Gene Name
DHTKD1
UniProt Synonym Gene Names
KIAA1630
UniProt Entry Name
DHTK1_HUMAN

NCBI Description

This gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathways of several amino acids, including lysine. Mutations in this gene are associated with 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth Disease Type 2Q. [provided by RefSeq, May 2013]

Uniprot Description

DHTKD1: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the alpha-ketoglutarate dehydrogenase family.

Protein type: EC 1.2.4.2; Oxidoreductase

Chromosomal Location of Human Ortholog: 10p14

Cellular Component: cytosol; mitochondrial matrix; mitochondrion; oxoglutarate dehydrogenase complex

Molecular Function: oxoglutarate dehydrogenase (succinyl-transferring) activity

Biological Process: generation of precursor metabolites and energy; glyoxylate metabolic process; tricarboxylic acid cycle

Disease: 2-aminoadipic 2-oxoadipic Aciduria; Charcot-marie-tooth Disease, Axonal, Type 2q

Research Articles on DHTKD1

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Product Notes

The DHTKD1 dhtkd1 (Catalog #AAA7044987) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DHTKD1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DHTKD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the DHTKD1 dhtkd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DHTKD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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