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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human cervix using MBS768605 (DHRS4 antibody) at dilution of 1:100)

Rabbit DHRS4 Polyclonal Antibody | anti-DHRS4 antibody

DHRS4 Rabbit Polyclonal

Gene Names
DHRS4; CR; NRDR; PHCR; PSCD; SDR-SRL; SDR25C1; SDR25C2; SCAD-SRL
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
DHRS4; Polyclonal Antibody; DHRS4 Rabbit Polyclonal; anti-DHRS4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
199
Applicable Applications for anti-DHRS4 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
Dehydrogenase/reductase (SDR family) member 4
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human cervix using MBS768605 (DHRS4 antibody) at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human cervix using MBS768605 (DHRS4 antibody) at dilution of 1:100)

Western Blot (WB)

(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS768605 (DHRS4 antibody) at dilution of 1:400)

Western Blot (WB) (HepG2 cells were subjected to SDS PAGE followed by western blot with MBS768605 (DHRS4 antibody) at dilution of 1:400)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23,917 Da
NCBI Official Full Name
dehydrogenase/reductase SDR family member 4 isoform 5
NCBI Official Synonym Full Names
dehydrogenase/reductase 4
NCBI Official Symbol
DHRS4
NCBI Official Synonym Symbols
CR; NRDR; PHCR; PSCD; SDR-SRL; SDR25C1; SDR25C2; SCAD-SRL
NCBI Protein Information
dehydrogenase/reductase SDR family member 4
UniProt Protein Name
Dehydrogenase/reductase SDR family member 4
UniProt Gene Name
DHRS4
UniProt Synonym Gene Names
SDR25C2; CR; PHCR; NRDR; humNRDR; PSCD
UniProt Entry Name
DHRS4_HUMAN

Uniprot Description

DHRS4: Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co- factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Cofactor and Vitamin Metabolism - retinol; Oxidoreductase; EC 1.1.1.184

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; mitochondrion; nuclear membrane; nucleus; peroxisomal membrane; peroxisome

Molecular Function: 3-keto sterol reductase activity; alcohol dehydrogenase [NAD(P)+] activity; carbonyl reductase (NADPH) activity; oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; receptor binding

Biological Process: alcohol metabolic process; ketone metabolic process; protein tetramerization; retinol metabolic process; steroid metabolic process

Research Articles on DHRS4

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Product Notes

The DHRS4 dhrs4 (Catalog #AAA768605) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DHRS4 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DHRS4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the DHRS4 dhrs4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DHRS4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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