Western Blot (WB)
(mouse stomach tissue were subjected to SDS PAGE followed by western blot with MBS768565 (DENND3 Antibody) at dilution of 1:1000)
Rabbit anti-Human, Mouse DENND3 Polyclonal Antibody | anti-DENND3 antibody
DENND3 Rabbit Polyclonal
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
>=95% as determined by SDS-PAGEImmunogen Affinity Purified
Synonyms
DENND3; Polyclonal Antibody; DENND3 Rabbit Polyclonal; DENN/MADD domain containing 3; KIAA0870; anti-DENND3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Human, Mouse; other species are not tested. Please decide the specificity by homology
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
1146
Applicable Applications for anti-DENND3 antibody
ELISA, WB
Application Notes
WB : 1:500-1:5000
Immunogen
DENN/MADD domain containing 3
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3
Preparation and Storage
Store at -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
Western Blot (WB)
(mouse stomach tissue were subjected to SDS PAGE followed by western blot with MBS768565 (DENND3 Antibody) at dilution of 1:1000)
Western Blot (WB)
(mouse stomach tissue were subjected to SDS PAGE followed by western blot with MBS768565 (DENND3 Antibody) at dilution of 1:1000)
Related Product Information for anti-DENND3 antibody
Guanine nucleotide exchange factor (GEF) activating RAB12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
136kDa
NCBI Official Full Name
DENND3 protein
NCBI Official Synonym Full Names
DENN domain containing 3
NCBI Official Symbol
DENND3
NCBI Protein Information
DENN domain-containing protein 3
UniProt Protein Name
DENN domain-containing protein 3
Protein Family
UniProt Gene Name
DENND3
UniProt Synonym Gene Names
KIAA0870
UniProt Entry Name
DEND3_HUMAN
Uniprot Description
DENND3: a guanine nucleotide exchange factor (GEF) activating RAB12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Plays a role in protein transport from recycling endosomes to lysosomes regulating, for example, the degradation of the transferrin receptor. Four isoforms of the human protein are produced by alternative splicing.
Protein type: GEFs; GEFs, Rab
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: intracellular
Molecular Function: Rab guanyl-nucleotide exchange factor activity
Biological Process: cellular protein catabolic process; endosome to lysosome transport; positive regulation of GTPase activity
Research Articles on DENND3
Similar Products
Product Notes
The DENND3 dennd3 (Catalog #AAA768565) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DENND3 Rabbit Polyclonal reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DENND3 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB. WB : 1:500-1:5000. Researchers should empirically determine the suitability of the DENND3 dennd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DENND3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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