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Testing Data (Mouse brain lysate probed with Rabbit anti Mouse Delta-Like Protein 3 followed by Sheep anti Rabbit IgG:HRP)

Rabbit anti-Mouse Delta-Like Protein 3 Polyclonal Antibody | anti-DLL3 antibody

Delta-Like Protein 3 (DLL3) (MaxLight 650)

Gene Names
Dll3; pu; pudgy
Reactivity
Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
Delta-Like Protein 3; Polyclonal Antibody; Delta-Like Protein 3 (DLL3) (MaxLight 650); anti-DLL3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse DLL3.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight650.
Applicable Applications for anti-DLL3 antibody
FLISA, Western Blot (WB)
Application Notes
WB: 1:100-1:500
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide corresponding to CSPEHGYCEEPDE aa222-234 of mouse DLL3 conjugated to KLH.
Conjugate
MaxLight650
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Testing Data

(Mouse brain lysate probed with Rabbit anti Mouse Delta-Like Protein 3 followed by Sheep anti Rabbit IgG:HRP)

Testing Data (Mouse brain lysate probed with Rabbit anti Mouse Delta-Like Protein 3 followed by Sheep anti Rabbit IgG:HRP)
Product Categories/Family for anti-DLL3 antibody
References
1. Bray, S.J. (2006). Notch signalling: a simple pathway becomes complex. Nat. Rev. Mol. Cell Biol. 7: 678-689.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
61,125 Da
NCBI Official Full Name
delta-like protein 3
NCBI Official Synonym Full Names
delta-like 3 (Drosophila)
NCBI Official Symbol
Dll3
NCBI Official Synonym Symbols
pu; pudgy
NCBI Protein Information
delta-like protein 3; delta3; M-Delta-3; drosophila Delta homolog 3
UniProt Protein Name
Delta-like protein 3
Protein Family
UniProt Gene Name
Dll3
UniProt Synonym Gene Names
Delta3; M-Delta-3
UniProt Entry Name
DLL3_MOUSE

Uniprot Description

DLL3: Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Can bind and activate Notch-1 or another Notch receptor.

Protein type: Membrane protein, integral; Cell development/differentiation

Cellular Component: membrane; integral to membrane

Molecular Function: protein binding; Notch binding

Biological Process: paraxial mesoderm development; nervous system development; tissue development; Notch signaling pathway; somitogenesis; positive regulation of neurogenesis; in utero embryonic development; multicellular organismal development; cell fate determination; negative regulation of neurogenesis; compartment specification; negative regulation of astrocyte differentiation; negative regulation of Notch signaling pathway; cell differentiation; skeletal development

Research Articles on DLL3

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Product Notes

The DLL3 dll3 (Catalog #AAA6444115) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Delta-Like Protein 3 (DLL3) (MaxLight 650) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Delta-Like Protein 3 can be used in a range of immunoassay formats including, but not limited to, FLISA, Western Blot (WB). WB: 1:100-1:500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the DLL3 dll3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Delta-Like Protein 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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