Rabbit Deformed Epidermal Autoregulatory Factor 1 Polyclonal Antibody | anti-DEAF1 antibody
Deformed Epidermal Autoregulatory Factor 1 Antibody FITC
Gene Names
Deaf1; NUDR; AU042387; C230009B13Rik
Reactivity
Mouse, RatPredicted: Human
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Purity
Immobilized antigen affinity chromatography
Synonyms
Deformed Epidermal Autoregulatory Factor 1; Polyclonal Antibody; Deformed Epidermal Autoregulatory Factor 1 Antibody FITC; FITC-Conjugated Deformed epidermal autoregulatory factor 1 homolog Antibody; Deaf1 antibody; DEAF1 transcription factor antibody; Deformed epidermal autoregulatory factor 1 homolog antibody; Nuclear DEA1 related transcriptional regulator antibody; NUDR antibody; SPN antibody; Suppressin antibody; Zinc finger MYND domain containing protein 5 antibody; ZMYND5 antibody; anti-DEAF1 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Predicted: Human
Predicted: Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immobilized antigen affinity chromatography
Concentration
0.5-1.5 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
566
Applicable Applications for anti-DEAF1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC)
Application Notes
ELISA: 1:10,000
ICC: 1:50-1:150
IHC: 1:50-1:150
IP: 1:200
WB: 1:500
ICC: 1:50-1:150
IHC: 1:50-1:150
IP: 1:200
WB: 1:500
Immunogen
Synthetic peptide taken within amino acid region 500-565 on mouse Deformed epidermal autoregulatory factor 1 homolog protein.
Conjugation
FITC
Molecular Function
DNA binding; metal ion binding; transcription factor activity; sequence-specific DNA binding
Subcellular Location
Cytoplasm; Nucleus; Secreted
Preparation and Storage
Store at -20 degree C for long term storage.
Related Product Information for anti-DEAF1 antibody
Overview: Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase. Required for neural tube closure and skeletal patterning. Regulates epithelial cell proliferation and side-branching in the mammary gland. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 4. Isoform 4 may inhibit transcriptional activity of isoform 1 by interacting with isoform 1 and retaining it in the cytoplasm. Transcriptional activator of EIF4G3.
Structure: Zinc-finger
Expression: Expressed in various tissues and cells such as in peripheral mononuclear cells and hormone-secreting pituitary cells. Expression in pancreatic lymph nodes of patients with type 1 diabetes is 20 times higher than in healthy controls. Highly expressed in fetal and adult brain.
Structure: Zinc-finger
Expression: Expressed in various tissues and cells such as in peripheral mononuclear cells and hormone-secreting pituitary cells. Expression in pancreatic lymph nodes of patients with type 1 diabetes is 20 times higher than in healthy controls. Highly expressed in fetal and adult brain.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,737 Da
NCBI Official Full Name
deformed epidermal autoregulatory factor 1 homolog isoform 1
NCBI Official Synonym Full Names
DEAF1, transcription factor
NCBI Official Symbol
Deaf1
NCBI Official Synonym Symbols
NUDR; AU042387; C230009B13Rik
NCBI Protein Information
deformed epidermal autoregulatory factor 1 homolog
UniProt Protein Name
Deformed epidermal autoregulatory factor 1 homolog
Protein Family
UniProt Gene Name
Deaf1
UniProt Synonym Gene Names
NUDR
Uniprot Description
Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction (). Regulates epithelial cell proliferation and side-branching in the mammary gland. Required for neural tube closure and skeletal patterning. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 2. Isoform 2 may inhibit transcriptional activity of isoform 1 by interacting with it and retaining it in the cytoplasm. Transcriptional activator of EIF4G3 (). May also involved in behavior (PubMed:24726472).
Research Articles on DEAF1
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Product Notes
The DEAF1 deaf1 (Catalog #AAA5400382) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Deformed Epidermal Autoregulatory Factor 1 Antibody FITC reacts with Mouse, Rat Predicted: Human and may cross-react with other species as described in the data sheet. AAA Biotech's Deformed Epidermal Autoregulatory Factor 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB), Immunocytochemistry (ICC). ELISA: 1:10,000 ICC: 1:50-1:150 IHC: 1:50-1:150 IP: 1:200 WB: 1:500. Researchers should empirically determine the suitability of the DEAF1 deaf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Deformed Epidermal Autoregulatory Factor 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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