Immunohistochemistry (IHC)
(Anti-LY75 / DEC-205 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Rabbit anti-Human DEC-205 / CD205 / LY75 Polyclonal Antibody | anti-DEC-205 antibody
Rabbit Polyclonal to Human DEC-205 / CD205 / LY75
Gene Names
LY75; CD205; LY-75; CLEC13B; DEC-205; GP200-MR6
Reactivity
Human
Applications
Immunohistochemistry
Purity
Purified
Synonyms
DEC-205 / CD205 / LY75; Polyclonal Antibody; Rabbit Polyclonal to Human DEC-205 / CD205 / LY75; Anti-DEC-205 / CD205 / LY75 Antibody (C-Terminus) IHC-plus; LY75; CD205; CLEC13B; CD205 antigen; LY-75; Lymphocyte antigen 75; DEC-205; gp200-MR6; Human DEC-205; anti-DEC-205 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Purified
Form/Format
20 mM Tris-HCl, pH 8.0, 20 mg/ml BSA, 0.05% sodium azide
Concentration
1.2 mg/ml (varies by lot)
Sequence Length
1722
Applicable Applications for anti-DEC-205 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
Peptide derived from C-terminal sequence of human CD205.
Immunogen
DEC-205 / CD205 / LY75 antibody was raised against peptide derived from C-terminal sequence of human CD205.
Antigen Modification
C-Terminus
Preparation and Storage
Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Anti-LY75 / DEC-205 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Immunohistochemistry (IHC)
(Anti-LY75 / DEC-205 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Related Product Information for anti-DEC-205 antibody
LY75/CD205/DEC-205 is an integral membrane protein homologous to the macrophage mannose receptor and functions as an antigen-uptake receptor on dendritic cells. DEC-205 is rapidly taken up by means of coated pits and vesicles and is delivered to a multivesicular endosomal compartment that resembles the MHC class II-containing vesicles.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,183 Da
NCBI Official Full Name
lymphocyte antigen 75
NCBI Official Synonym Full Names
lymphocyte antigen 75
NCBI Official Symbol
LY75
NCBI Official Synonym Symbols
CD205; LY-75; CLEC13B; DEC-205; GP200-MR6
NCBI Protein Information
lymphocyte antigen 75; C-type lectin domain family 13 member B
UniProt Protein Name
Lymphocyte antigen 75
UniProt Gene Name
LY75
UniProt Synonym Gene Names
CD205; CLEC13B; Ly-75
UniProt Entry Name
LY75_HUMAN
Uniprot Description
LY75: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment. Causes reduced proliferation of B-lymphocytes. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q24
Cellular Component: integral to plasma membrane
Molecular Function: receptor activity; carbohydrate binding
Biological Process: immune response; endocytosis; inflammatory response
Research Articles on DEC-205
Similar Products
Product Notes
The DEC-205 ly75 (Catalog #AAA245310) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human DEC-205 / CD205 / LY75 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DEC-205 / CD205 / LY75 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (10 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the DEC-205 ly75 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DEC-205 / CD205 / LY75, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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