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SDS-Page (Gel: 8%SDS-PAGE Lysate: 40 μg, Lane 1-2: HEPG2 and Hela cell lysates Primary antibody:CREB3L2 Antibody at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 30 seconds)

Rabbit anti-Human DDHD1 Polyclonal Antibody | anti-DDHD1 antibody

DDHD1 Antibody

Gene Names
DDHD1; SPG28; PAPLA1; PA-PLA1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
DDHD1; Polyclonal Antibody; DDHD1 Antibody; SPG28; PAPLA1; PA-PLA1; anti-DDHD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total DDHD1 protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.6mg/ml (varies by lot)
Sequence Length
900
Applicable Applications for anti-DDHD1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB:1:200-1000
IF: 1: 20-100
Immunogen
Synthetic peptide of human DDHD1
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.

SDS-Page

(Gel: 8%SDS-PAGE Lysate: 40 μg, Lane 1-2: HEPG2 and Hela cell lysates Primary antibody:CREB3L2 Antibody at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 30 seconds)

SDS-Page (Gel: 8%SDS-PAGE Lysate: 40 μg, Lane 1-2: HEPG2 and Hela cell lysates Primary antibody:CREB3L2 Antibody at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 30 seconds)
Related Product Information for anti-DDHD1 antibody
This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Categories/Family for anti-DDHD1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
100 kDa
NCBI Official Full Name
phospholipase DDHD1 isoform c
NCBI Official Synonym Full Names
DDHD domain containing 1
NCBI Official Symbol
DDHD1
NCBI Official Synonym Symbols
SPG28; PAPLA1; PA-PLA1
NCBI Protein Information
phospholipase DDHD1
UniProt Protein Name
Phospholipase DDHD1
Protein Family
UniProt Gene Name
DDHD1
UniProt Synonym Gene Names
KIAA1705; PA-PLA1

NCBI Description

This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]

Uniprot Description

Phospholipase that hydrolyzes phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid. The different isoforms may change the substrate specificity.

Research Articles on DDHD1

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Product Notes

The DDHD1 ddhd1 (Catalog #AAA9429984) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DDHD1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DDHD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB:1:200-1000 IF: 1: 20-100. Researchers should empirically determine the suitability of the DDHD1 ddhd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DDHD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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