Immunohistochemistry (IHC)
(Anti-CYBRD1 / DCYTB antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)
Goat DCYTB / CYBRD1 Polyclonal Antibody | anti-DCYTB antibody
Goat Polyclonal to Human DCYTB / CYBRD1
Predicted Reactivity: Monkey, Pig, Rabbit (at least 90% immunogen sequence identity)
Predicted Reactivity: Monkey, Pig, Rabbit (at least 90% immunogen sequence identity)
Immunohistochemistry (IHC)
(Anti-CYBRD1 / DCYTB antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-CYBRD1 / DCYTB antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-CYBRD1 / DCYTB antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)
Immunohistochemistry (IHC)
(Anti-CYBRD1 / DCYTB antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq, Jul 2008]
Uniprot Description
CYBRD1: Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.-.-.-; Transporter; Transporter, ion channel; Motility/polarity/chemotaxis; Membrane protein, multi-pass; Transporter, iron; Oxidoreductase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q31.1
Cellular Component: brush border membrane; integral to membrane; plasma membrane
Molecular Function: oxidoreductase activity, oxidizing metal ions; metal ion binding; ferric-chelate reductase activity
Biological Process: cellular iron ion homeostasis; response to iron ion; transmembrane transport
Research Articles on DCYTB
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Product Notes
The DCYTB cybrd1 (Catalog #AAA247719) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human DCYTB / CYBRD1 reacts with Gibbon, Gorilla, Human, Orangutan Predicted Reactivity: Monkey, Pig, Rabbit (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's DCYTB / CYBRD1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA). ELISA (1:16000), IHC-P (2.5 ug/ml). Researchers should empirically determine the suitability of the DCYTB cybrd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DCYTB / CYBRD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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