Rabbit anti-Human DCTN6 Polyclonal Antibody | anti-DCTN6 antibody

DCTN6, ID (DCTN6, WS3, Dynactin subunit 6, Dynactin subunit p27, Protein WS-3) (Biotin)

Cat. Num. AAA6291235

• Gene Names: DCTN6; WS3; p27; WS-3
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: DCTN6; Polyclonal Antibody; ID (DCTN6; WS3; Dynactin subunit 6; Dynactin subunit p27; Protein WS-3) (Biotin); Protein WS-3; anti-DCTN6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-DCTN6 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: DCTN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the Central region of human DCTN6.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(DCTN6 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the DCTN6 antibody detected the DCTN6 protein (arrow).)

Related Product Information for anti-DCTN6 antibody

The protein encoded by this gene contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known.

Product Categories/Family for anti-DCTN6 antibody

Antibodies; Proteins

References

Lamesch, P., et al. Genomics 89(3):307-315(2007). Parisi, G., et al. FEBS Lett. 562 (1-3), 1-4 (2004): Eckley, D.M., et al. J. Cell Biol. 147(2):307-320(1999). Murdock, D.G., et al. J. Biol. Chem. 274(20):14429-14433(1999). Ichikawa, K., et al. Gene 189(2):277-287(1997).

NCBI and Uniprot Product Information

• NCBI GI #: 5730116
• NCBI GeneID: 10671
• NCBI Accession #: NP_006562.1
• NCBI GenBank Nucleotide #: NM_006571.3
• UniProt Accession #: O00399; B2RAC1
• Molecular Weight: 20,747 Da
• NCBI Official Full Name: dynactin subunit 6
• NCBI Official Synonym Full Names: dynactin subunit 6
• NCBI Official Symbol: DCTN6
• NCBI Official Synonym Symbols: WS3; p27; WS-3
• NCBI Protein Information: dynactin subunit 6
• UniProt Protein Name: Dynactin subunit 6
• UniProt Gene Name: DCTN6
• UniProt Synonym Gene Names: WS3
• UniProt Entry Name: DCTN6_HUMAN

Uniprot Description

dynactin 6: contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known. [provided by RefSeq, Jul 2008]

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 8p12

Cellular Component: centrosome; cytosol

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; ER to Golgi vesicle-mediated transport