Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7045692 at dilution of 1:100)
Rabbit anti-Human DCTN3 Polyclonal Antibody | anti-DCTN3 antibody
DCTN3 Antibody
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7045692 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human pancreatic tissue using MBS7045692 at dilution of 1:100)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Uniprot Description
dynactin 3: Together with dynein may be involved in spindle assembly and cytokinesis. Belongs to the dynactin subunit 3 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motor; Microtubule-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 9p13
Cellular Component: centrosome; cytosol; dynactin complex; perinuclear region of cytoplasm
Molecular Function: protein binding; structural molecule activity
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; cytokinesis; ER to Golgi vesicle-mediated transport; G2/M transition of mitotic cell cycle
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Product Notes
The DCTN3 dctn3 (Catalog #AAA7045692) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DCTN3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DCTN3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC: 1:20-1:200. Researchers should empirically determine the suitability of the DCTN3 dctn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DCTN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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