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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human colon cancer tissue using DCAF6 Polyclonal Antibody at dilution 1:50)

Rabbit DCAF6 Polyclonal Antibody | anti-DCAF6 antibody

DCAF6 Polyclonal Antibody

Gene Names
DCAF6; NRIP; ARCAP; IQWD1; PC326; MSTP055; 1200006M05Rik
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
DCAF6; Polyclonal Antibody; DCAF6 Polyclonal Antibody; NRIP; ARCAP; IQWD1; PC326; MSTP055; 1200006M05Rik; anti-DCAF6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.9mg/mL (varies by lot)
Sequence Length
860
Applicable Applications for anti-DCAF6 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human DCAF6
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using DCAF6 Polyclonal Antibody at dilution 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human colon cancer tissue using DCAF6 Polyclonal Antibody at dilution 1:50)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human brain tissue using DCAF6 Polyclonal Antibody at dilution 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human brain tissue using DCAF6 Polyclonal Antibody at dilution 1:50)
Related Product Information for anti-DCAF6 antibody
NRIP (Nuclear receptor interaction protein), also known as IQWD1 (IQ motif and WD repeat-containing protein 1), MSTP055, ARCAP or PC326, is an 860 amino acid protein that localizes to the nucleus and contains one IQ domain and seven WD-repeats. Expressed in testis, skeletal muscle, prostate and heart, NRIP functions as a ligand-dependent coactivator of nuclear receptors and specifically enhances the transcriptional activity of AR (androgen receptor) and GR (glucocorticoid receptor). NRIP exists as three isoforms that are produced by alternative splicing events.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
103,070 Da
NCBI Official Full Name
DDB1- and CUL4-associated factor 6
NCBI Official Synonym Full Names
DDB1 and CUL4 associated factor 6
NCBI Official Symbol
DCAF6
NCBI Official Synonym Symbols
NRIP; ARCAP; IQWD1; PC326; MSTP055; 1200006M05Rik
NCBI Protein Information
DDB1- and CUL4-associated factor 6; IQ motif and WD repeat-containing protein 1; IQ motif and WD repeats 1; androgen receptor complex-associated protein; nuclear receptor interaction protein
UniProt Protein Name
DDB1- and CUL4-associated factor 6
UniProt Gene Name
DCAF6
UniProt Synonym Gene Names
IQWD1; ARCAP; NRIP
UniProt Entry Name
DCAF6_HUMAN

Uniprot Description

MSTP055: Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 1q24.2

Cellular Component: nucleoplasm; focal adhesion; cytoplasm; nucleus

Molecular Function: ligand-dependent nuclear receptor transcription coactivator activity

Biological Process: protein ubiquitination; positive regulation of transcription from RNA polymerase II promoter

Research Articles on DCAF6

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Product Notes

The DCAF6 dcaf6 (Catalog #AAA2523273) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DCAF6 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DCAF6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the DCAF6 dcaf6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DCAF6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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