Rabbit anti-Human DAZ1 Polyclonal Antibody | anti-DAZ1 antibody

DAZ1 Antibody

Cat. Num. AAA9429970

• Gene Names: DAZ1; DAZ; SPGY
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: DAZ1; Polyclonal Antibody; DAZ1 Antibody; DAZ; SPGY; anti-DAZ1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: The antibody detects endogenous levels of total DAZ1 protein.
• Purity/Purification: Antigen affinity purification
• Form/Format: In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Concentration: 1.4mg/ml (varies by lot)
• Sequence Length: 2382

• Applicable Applications for anti-DAZ1 antibody: Immunohistochemistry (IHC)
• Application Notes: IF: 1: 40-200
• Immunogen: Fusion protein of human DAZ1
• Immunogen Type: Protein
• Preparation and Storage: Store at -20 degree C.

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 46981(CPNE7 Antibody) at dilution 1/20. (Original magnification: 200))

Related Product Information for anti-DAZ1 antibody

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described; thus the RefSeq for this gene contains only two RRM domains.

Product Categories/Family for anti-DAZ1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 92097598
• NCBI GeneID: 1617
• UniProt Accession #: Q9NQZ3; Q1RMF9; Q9NQZ4
• Molecular Weight: 67,295 Da
• NCBI Official Full Name: Homo sapiens deleted in azoospermia 1, mRNA
• NCBI Official Synonym Full Names: deleted in azoospermia 1
• NCBI Official Symbol: DAZ1
• NCBI Official Synonym Symbols: DAZ; SPGY
• NCBI Protein Information: deleted in azoospermia protein 1
• UniProt Protein Name: Deleted in azoospermia protein 1
• Protein Family: Deleted in azoospermia protein
• UniProt Gene Name: DAZ1
• UniProt Synonym Gene Names: DAZ; SPGY

NCBI Description

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains three copies of the 10.8 kb repeat. However, no transcripts containing three copies of the RRM domain have been described; thus the RefSeq for this gene contains only two RRM domains. [provided by RefSeq, Jul 2008]

Uniprot Description

RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells.