Rabbit anti-Mouse Damage Specific DNA Binding Protein 2 (DDB2) Polyclonal Antibody | anti-DDB2 antibody
APC/CY7-Linked Polyclonal Antibody to Damage Specific DNA Binding Protein 2 (DDB2)
Reactivity
Mouse
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Synonyms
Damage Specific DNA Binding Protein 2 (DDB2); Polyclonal Antibody; APC/CY7-Linked Polyclonal Antibody to Damage Specific DNA Binding Protein 2 (DDB2); DDBB; UV-DDB2; Xeroderma Pigmentosum Group E Protein; UV-Damaged DNA-Binding Protein 2; DDB p48 Subunit; Damage-specific DNA-binding protein 2; anti-DDB2 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Concentration
>=100ug/ml (varies by lot)
Applicable Applications for anti-DDB2 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
Immunogen
DDB2 (Lys212~Leu407)
Conjugation
APC-Cy7
Cross Reactivity
Mouse
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2032906
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56,609 Da
NCBI Official Full Name
DNA damage-binding protein 2
NCBI Official Synonym Full Names
damage-specific DNA binding protein 2
NCBI Official Symbol
ddb2
NCBI Protein Information
DNA damage-binding protein 2
UniProt Protein Name
DNA damage-binding protein 2
Protein Family
UniProt Gene Name
ddb2
Uniprot Description
Required for DNA repair. Binds to ddb1 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. Also appears to function as the substrate recognition module for a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex which may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair ().
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Product Notes
The DDB2 ddb2 (Catalog #AAA2041030) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The APC/CY7-Linked Polyclonal Antibody to Damage Specific DNA Binding Protein 2 (DDB2) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Damage Specific DNA Binding Protein 2 (DDB2) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the DDB2 ddb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Damage Specific DNA Binding Protein 2 (DDB2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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