Western Blot (WB)
(Western blot analysis of DAF in A549 cell lysate with DAF antibody at 1 μg/ml.)
Rabbit anti-Human DAF Polyclonal Antibody | anti-CD55 antibody
DAF Antibody
Western Blot (WB)
(Western blot analysis of DAF in A549 cell lysate with DAF antibody at 1 μg/ml.)
Western Blot (WB)
(Western blot analysis of DAF in A549 cell lysate with DAF antibody at 1 μg/ml.)
Immunohistochemistry (IHC)
(Immunohistochemistry of DAF in human lung tissue with DAF antibody at 5 μg/ml.)
Immunohistochemistry (IHC)
(Immunohistochemistry of DAF in human lung tissue with DAF antibody at 5 μg/ml.)
Immunofluorescence (IF)
(Immunofluorescence of DAF in human lung tissue with DAF antibody at 20 μg/ml.)
Immunofluorescence (IF)
(Immunofluorescence of DAF in human lung tissue with DAF antibody at 20 μg/ml.)
Western Blot (WB)
(Western blot analysis of DAF1 expression in HeLa cell lysate with DAF1 antibody at (A) 1 and (B) 2 μg/ml.)
Western Blot (WB)
(Western blot analysis of DAF1 expression in HeLa cell lysate with DAF1 antibody at (A) 1 and (B) 2 μg/ml.)
NCBI and Uniprot Product Information
Observed: 49 kDa
NCBI Description
This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014]
Uniprot Description
CD55: This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Belongs to the receptors of complement activation (RCA) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, GPI anchor; Cell surface
Chromosomal Location of Human Ortholog: 1q32
Cellular Component: cell surface; integral to plasma membrane; extracellular region; plasma membrane; lipid raft
Molecular Function: viral receptor activity; protein binding; lipid binding
Biological Process: respiratory burst; elevation of cytosolic calcium ion concentration; entry of virus into host cell; negative regulation of complement activation; regulation of complement activation; innate immune response; complement activation, classical pathway; regulation of lipopolysaccharide-mediated signaling pathway
Disease: Blood Group, Cromer System
Research Articles on CD55
Similar Products
Product Notes
The CD55 cd55 (Catalog #AAA153461) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DAF Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DAF can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). DAF body can be used for detection of DAF by Western blot at 1 - 2 mug/ml. Antibody can also be used for Immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the CD55 cd55 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DAF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
