Rabbit anti-Human, Mouse DACT3 Polyclonal Antibody | anti-DACT3 antibody
DACT3 Antibody
Gene Names
DACT3; RRR1; DAPPER3
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
DACT3; Polyclonal Antibody; DACT3 Antibody; Antagonist of beta-catenin Dapper homolog 3; Arginine rich region 1; Arginine rich region 1 protein; Arginine-rich region 1 protein; Dact3; DACT3_HUMAN; Dapper antagonist of beta catenin 3; Dapper antagonist of beta catenin homolog 3 (Xenopus laevis); Dapper homolog 3; Dapper3; Dpr3; RRR1; Thymus expressed gene 3 like; anti-DACT3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
DACT3 Antibody detects endogenous levels of DACT3.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-DACT3 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human DACT3.
Conjugation
Unconjugated
Similarity
The C-terminal PDZ-binding motif may mediate interaction with the PDZ domains of DSH (Dishevelled) family proteins. Belongs to the dapper family.
Subunit Structure
Can form homodimers and heterodimers with DACT1 or DACT3. Interacts with CSNK1D, PKA catalytic subunit, PKC-type kinase, DVL1, DVL3, VANGL1, VANGL2 and CTNND1 (By similarity). Interacts with DVL2.
Function
May be involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-DACT3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
64,949 Da
NCBI Official Full Name
Dapper homolog 3
NCBI Official Synonym Full Names
dishevelled-binding antagonist of beta-catenin 3
NCBI Official Symbol
DACT3
NCBI Official Synonym Symbols
RRR1; DAPPER3
NCBI Protein Information
dapper homolog 3; antagonist of beta-catenin Dapper homolog 3; arginine-rich region 1 protein; dapper, antagonist of beta-catenin, homolog 3
UniProt Protein Name
Dapper homolog 3
Protein Family
UniProt Gene Name
DACT3
UniProt Synonym Gene Names
RRR1
UniProt Entry Name
DACT3_HUMAN
Uniprot Description
DACT3: May be involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. Belongs to the dapper family.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 19q13.32
Cellular Component: cytoplasm
Molecular Function: identical protein binding; protein kinase C binding; protein kinase A binding
Biological Process: Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; negative regulation of cell growth
Research Articles on DACT3
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Product Notes
The DACT3 dact3 (Catalog #AAA9631065) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DACT3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DACT3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the DACT3 dact3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DACT3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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