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Testing Data

Rabbit anti-Human D4 GDI Polyclonal Antibody | anti-D4 GDI antibody

D4 GDI Antibody

Gene Names
ARHGDIB; D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; RhoGDI2
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
D4 GDI; Polyclonal Antibody; D4 GDI Antibody; anti-D4 GDI antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Form/Format
Purified by peptide affinity column containing 2% BSA and 0.02% NaN3
Sequence Length
201
Applicable Applications for anti-D4 GDI antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Peptide ELISA: 1:40,000-1:80,000
WB: 1:200-1:1,000
IHC: 1:50-1:200
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.

Testing Data

Testing Data

Testing Data

Testing Data
Related Product Information for anti-D4 GDI antibody
Rabbit polyclonal D4 GDI (1) antibody was raised against a peptide from the N terminal residues of human D4 GDI protein.
References
(1) Wu, Y., Moissoglu, K., Wang, H., Wang, X., et al.Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function. Proc. Natl. Acad. Sci. U.S.A. 106 (14), 5807-5812 (2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
397
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,988 Da
NCBI Official Full Name
rho GDP-dissociation inhibitor 2
NCBI Official Synonym Full Names
Rho GDP dissociation inhibitor beta
NCBI Official Symbol
ARHGDIB
NCBI Official Synonym Symbols
D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; RhoGDI2
NCBI Protein Information
rho GDP-dissociation inhibitor 2
UniProt Protein Name
Rho GDP-dissociation inhibitor 2
UniProt Gene Name
ARHGDIB
UniProt Synonym Gene Names
GDIA2; GDID4; RAP1GN1; Rho GDI 2

NCBI Description

Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010]

Uniprot Description

Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).

Research Articles on D4 GDI

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Product Notes

The D4 GDI arhgdib (Catalog #AAA851875) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The D4 GDI Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's D4 GDI can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA: 1:40,000-1:80,000 WB: 1:200-1:1,000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the D4 GDI arhgdib for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "D4 GDI, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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