Western Blot (WB)
(Western Blot:Sample: Recombinant CYFRA21-1, Human.)
Rabbit Cytokeratin Fragment Antigen 21-1 Polyclonal Antibody | anti-CYFRA21-1 antibody
Polyclonal Antibody to Cytokeratin Fragment Antigen 21-1 (CYFRA21-1)
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot:Sample: Recombinant CYFRA21-1, Human.)
Western Blot (WB)
(Western Blot:Sample: Recombinant CYFRA21-1, Human.)
Western Blot (WB)
(Western Blot:Sample:Lane 1: Human Serum;Lane 2: Human MCF-7 Cells;Lane 3: Human A431 Cells;Lane 4: Human HepG2 Cells.)
Western Blot (WB)
(Western Blot:Sample:Lane 1: Human Serum;Lane 2: Human MCF-7 Cells;Lane 3: Human A431 Cells;Lane 4: Human HepG2 Cells.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Breast cancer Tissue;Primary Ab: 10ug/ml Rabbit Anti-Human CYFRA21-1 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody(Catalog: MBS2086047))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Breast cancer Tissue;Primary Ab: 10ug/ml Rabbit Anti-Human CYFRA21-1 AntibodySecond Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody(Catalog: MBS2086047))
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Prostate Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Prostate Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Stomach Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P;Samples: Human Stomach Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-PSamples: Human Breast cancer TissuePrimary Ab: 10ug/ml Rabbit Anti-Human CYFRA21-1 Antibody Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG PolyclonalAntibody (Catalog: MBS2086047))
Immunohistochemistry (IHC)
(DAB staining on IHC-PSamples: Human Breast cancer TissuePrimary Ab: 10ug/ml Rabbit Anti-Human CYFRA21-1 Antibody Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG PolyclonalAntibody (Catalog: MBS2086047))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Uniprot Description
K19: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 19 differs from all other IF proteins in lacking the C-terminal tail domain. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17q21.2
Cellular Component: apicolateral plasma membrane; cell periphery; costamere; cytosol; dystrophin-associated glycoprotein complex; extracellular exosome; intermediate filament; plasma membrane; sarcolemma; terminal web; Z disc
Molecular Function: protein binding; protein complex binding; structural constituent of cytoskeleton; structural constituent of muscle
Biological Process: cornification; keratinization; Notch signaling pathway; response to estrogen; sarcomere organization; viral process
Research Articles on CYFRA21-1
Similar Products
Product Notes
The CYFRA21-1 krt19 (Catalog #AAA2028282) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Cytokeratin Fragment Antigen 21-1 (CYFRA21-1) reacts with Homo sapiens (Human) and may cross-react with other species as described in the data sheet. AAA Biotech's Cytokeratin Fragment Antigen 21-1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the CYFRA21-1 krt19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin Fragment Antigen 21-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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