Western Blot (WB)
Rabbit Cytokeratin 17, CK17 Polyclonal Antibody | anti-CK17 antibody
Anti-Cytokeratin 17, CK17 antibody
Reactivity
Human, mouse, rat
Applications
Western Blot
Purity
Immunogen affinity purified
Synonyms
Cytokeratin 17; CK17; Polyclonal Antibody; Anti-Cytokeratin 17; CK17 antibody; Polyclonal Anti- Cytokeratin 17; anti-CK17 antibody
Host
Rabbit
Reactivity
Human, mouse, rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified
Form/Format
Liquid
Applicable Applications for anti-CK17 antibody
Western Blot (WB)
Application Notes
WB (1:500-1000)
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to the N-terminal residues of mouse Cytokeratin 17.
Storage Buffer
In TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide
Storage Buffer
In TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
Preparation and Storage
Store at 4 degree C after thawing (1 week). Aliquot and store at -20 degree C for long term (at least one year). Avoid repeated freeze and thaw cycles
Western Blot (WB)
Western Blot (WB)
Related Product Information for anti-CK17 antibody
Cytokeratin 17, also known as Keratin, type I cytoskeletal 17 (K17) is a protein that in humans is encoded by the KRT17 gene. Keratin 17 (K17) is a differentiation-specific keratin expressed in the nail bed, hair follicle, sebaceous gland and other epidermal appendages.1 The KRT17 gene is 5 kb long with 8 exons. Mutations in the gene encoding this protein lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. Cytokeratin 17 synthesis seems to be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells".2
References
1. Covello, S. P., Smith, F. J. D., Sillevis Smitt, J. H., Paller, A. S., Munro, C. S., Jonkman, M. F., Uitto, J., McLean, W. H. I. Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2. Brit. J. Derm. 139: 475-480, 1998. 2. Troyanovsky, S. M., Leube, R. E., Franke, W. W. Characterization of the human gene encoding cytokeratin 17 and its expression pattern. Europ. J. Cell Biol. 59: 127-137, 1992.
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Product Notes
The CK17 (Catalog #AAA355070) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Cytokeratin 17, CK17 antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's Cytokeratin 17, CK17 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1:500-1000). Researchers should empirically determine the suitability of the CK17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 17, CK17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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