Western Blot (WB)
(Western blot analysis of CYP51A1 Antibody (C-term) in HL-60 cell line lysates (35ug/lane). CYP51A1 (arrow) was detected using the purified Pab.)
Rabbit anti-Human CYP51A1 Polyclonal Antibody | anti-CYP51A1 antibody
CYP51A1, CT (Cytochrome P450-14DM, Cytochrome P45014DM, Sterol 14-alpha Demethylase, Cytochrome P450LI, CYPLI, Cytochrome P450 51A1, Lanosterol 14-alpha Demethylase, LDM, CYP51) (APC)
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of CYP51A1 Antibody (C-term) in HL-60 cell line lysates (35ug/lane). CYP51A1 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of CYP51A1 Antibody (C-term) in HL-60 cell line lysates (35ug/lane). CYP51A1 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with CYP51A1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with CYP51A1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
Uniprot Description
CYP51A1: Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; EC 1.14.13.70; Lipid Metabolism - steroid biosynthesis; Oxidoreductase
Chromosomal Location of Human Ortholog: 7q21.2
Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane
Molecular Function: sterol 14-demethylase activity; iron ion binding; heme binding
Biological Process: xenobiotic metabolic process; sterol metabolic process; cholesterol biosynthetic process; steroid biosynthetic process; cholesterol biosynthetic process via 24,25-dihydrolanosterol
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Product Notes
The CYP51A1 cyp51a1 (Catalog #AAA6471778) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CYP51A1, CT (Cytochrome P450-14DM, Cytochrome P45014DM, Sterol 14-alpha Demethylase, Cytochrome P450LI, CYPLI, Cytochrome P450 51A1, Lanosterol 14-alpha Demethylase, LDM, CYP51) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CYP51A1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:50-1:100 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the CYP51A1 cyp51a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CYP51A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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