Rabbit anti-Human CYP4F3 Polyclonal Antibody | anti-CYP4F3 antibody
CYP4F3 (N-Term) Rabbit pAb
FC/FACS: 1:10-50
NCBI and Uniprot Product Information
NCBI Description
This gene, CYP4F3, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2019]
Uniprot Description
CYP4F3: Cytochromes P450 are a group of heme-thiolate monooxygenases. This enzyme requires molecular oxygen and NADPH for the omega-hydroxylation of LTB4, a potent chemoattractant for polymorphonuclear leukocytes. Belongs to the cytochrome P450 family.
Protein type: EC 1.14.13.30; Oxidoreductase; Membrane protein, integral; Lipid Metabolism - arachidonic acid
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: endoplasmic reticulum membrane; integral to membrane
Molecular Function: leukotriene-B4 20-monooxygenase activity; iron ion binding; heme binding; monooxygenase activity
Biological Process: xenobiotic metabolic process; icosanoid metabolic process; arachidonic acid metabolic process; leukotriene metabolic process
Research Articles on CYP4F3
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Product Notes
The CYP4F3 cyp4f3 (Catalog #AAA8555318) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CYP4F3 (N-Term) Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CYP4F3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Flow Cytometry (FC/FACS). WB: 1:1000 FC/FACS: 1:10-50. Researchers should empirically determine the suitability of the CYP4F3 cyp4f3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CYP4F3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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