Western Blot (WB)
(Western blot analysis of anti-CYP2J2 Antibody (Center) in CEM cell line lysates (35ug/lane). CYP2J2 (arrow) was detected using the purified Pab.)
Rabbit anti-Human CYP2J2 Polyclonal Antibody | anti-CYP2J2 antibody
CYP2J2 Antibody (Center)
Western Blot (WB)
(Western blot analysis of anti-CYP2J2 Antibody (Center) in CEM cell line lysates (35ug/lane). CYP2J2 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-CYP2J2 Antibody (Center) in CEM cell line lysates (35ug/lane). CYP2J2 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(CYP2J2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CYP2J2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(CYP2J2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CYP2J2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
King L.M., Ma J., Srettabunjong S.Mol. Pharmacol. 61:840-852(2002)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. [provided by RefSeq, Jul 2008]
Uniprot Description
CYP2J2: This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools. Belongs to the cytochrome P450 family.
Protein type: Contractile; Lipid Metabolism - linoleic acid; Lipid Metabolism - arachidonic acid; Oxidoreductase; EC 1.14.14.1
Chromosomal Location of Human Ortholog: 1p31.3-p31.2
Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; cytoplasm
Molecular Function: arachidonic acid 14,15-epoxygenase activity; iron ion binding; arachidonic acid 11,12-epoxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; arachidonic acid epoxygenase activity; steroid hydroxylase activity; oxygen binding
Biological Process: xenobiotic metabolic process; exogenous drug catabolic process; icosanoid metabolic process; arachidonic acid metabolic process; linoleic acid metabolic process; epoxygenase P450 pathway; regulation of heart contraction
Research Articles on CYP2J2
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Product Notes
The CYP2J2 cyp2j2 (Catalog #AAA9210481) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 156-183. The CYP2J2 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CYP2J2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the CYP2J2 cyp2j2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CYP2J2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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