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Western Blot (WB) (CXXC1 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the CXXC1 antibody detected the CXXC1 protein (arrow).)

Rabbit anti-Human, Mouse CXXC1 Polyclonal Antibody | anti-CXXC1 antibody

CXXC1, ID (CXXC1, CFP1, CGBP, PCCX1, PHF18, CpG-binding protein, CXXC-type zinc finger protein 1, PHD finger and CXXC domain-containing protein 1)

Gene Names
CXXC1; CFP1; CGBP; SPP1; PCCX1; PHF18; hCGBP; ZCGPC1; HsT2645; 2410002I16Rik; 5830420C16Rik
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
CXXC1; Polyclonal Antibody; ID (CXXC1; CFP1; CGBP; PCCX1; PHF18; CpG-binding protein; CXXC-type zinc finger protein 1; PHD finger and CXXC domain-containing protein 1); Anti -CXXC1; anti-CXXC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Human, mouse
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-CXXC1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunogen
CXXC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the Central region of human CXXC1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(CXXC1 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the CXXC1 antibody detected the CXXC1 protein (arrow).)

Western Blot (WB) (CXXC1 Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the CXXC1 antibody detected the CXXC1 protein (arrow).)
Related Product Information for anti-CXXC1 antibody
Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001 [PubMed 11604496]).
Product Categories/Family for anti-CXXC1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
75,712 Da
NCBI Official Full Name
CXXC1 protein, partial
NCBI Official Synonym Full Names
CXXC finger protein 1
NCBI Official Symbol
CXXC1
NCBI Official Synonym Symbols
CFP1; CGBP; SPP1; PCCX1; PHF18; hCGBP; ZCGPC1; HsT2645; 2410002I16Rik; 5830420C16Rik
NCBI Protein Information
cpG-binding protein; CpG binding protein; CXXC finger 1 (PHD domain); CXXC-type zinc finger protein 1; zinc finger, CpG binding-type containing 1; PHD finger and CXXC domain-containing protein 1; DNA-binding protein with PHD finger and CXXC domain
UniProt Protein Name
CpG-binding protein
UniProt Gene Name
CXXC1
UniProt Synonym Gene Names
CFP1; CGBP; PCCX1; PHF18
UniProt Entry Name
CXXC1_HUMAN

NCBI Description

Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001 [PubMed 11604496]).[supplied by OMIM, Mar 2008]

Uniprot Description

CXXC1: Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 18q12

Cellular Component: nucleoplasm; histone methyltransferase complex; nuclear matrix; cytoplasm; nuclear speck; nucleus

Molecular Function: protein binding; zinc ion binding; unmethylated CpG binding; histone lysine N-methyltransferase activity (H3-K4 specific)

Biological Process: unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; transcription, DNA-dependent; regulation of transcription, DNA-dependent; unfolded protein response; positive regulation of transcription, DNA-dependent; histone H3-K4 methylation

Research Articles on CXXC1

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Product Notes

The CXXC1 cxxc1 (Catalog #AAA6011567) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CXXC1, ID (CXXC1, CFP1, CGBP, PCCX1, PHF18, CpG-binding protein, CXXC-type zinc finger protein 1, PHD finger and CXXC domain-containing protein 1) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CXXC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the CXXC1 cxxc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CXXC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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