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Rabbit anti-Human, Mouse CTNNBIP1 Polyclonal Antibody | anti-CTNNBIP1 antibody

CTNNBIP1 Antibody

Gene Names
CTNNBIP1; ICAT
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
CTNNBIP1; Polyclonal Antibody; CTNNBIP1 Antibody; Beta catenin interacting protein 1; Beta catenin interacting protein ICAT; Beta-catenin-interacting protein 1; Catenin beta interacting protein 1; CNBP1_HUMAN; CTNNBIP 1; ICAT; Inhibitor of beta catenin and Tcf 4; Inhibitor of beta-catenin and Tcf-4; MGC15093; anti-CTNNBIP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
CTNNBIP1 Antibody detects endogenous levels of total CTNNBIP1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CTNNBIP1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Similarity
Belongs to the CTNNBIP1 family.
Subunit Structure
Binds CTNNB1.
Function
Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-CTNNBIP1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9,170 Da
NCBI Official Full Name
beta-catenin-interacting protein 1
NCBI Official Synonym Full Names
catenin, beta interacting protein 1
NCBI Official Symbol
CTNNBIP1
NCBI Official Synonym Symbols
ICAT
NCBI Protein Information
beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; inhibitor of beta-catenin and Tcf-4
UniProt Protein Name
Beta-catenin-interacting protein 1
UniProt Gene Name
CTNNBIP1
UniProt Synonym Gene Names
ICAT
UniProt Entry Name
CNBP1_HUMAN

NCBI Description

The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

CTNNBIP1: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. Belongs to the CTNNBIP1 family.

Protein type: Cell development/differentiation; Inhibitor

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: nucleoplasm; cytoplasm; nucleus; beta-catenin destruction complex; cytosol

Molecular Function: protein binding; beta-catenin binding

Biological Process: anterior/posterior pattern formation; positive regulation of monocyte differentiation; positive regulation of osteoblast differentiation; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; ureteric bud branching; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; negative regulation of protein binding; regulation of vascular permeability during acute inflammatory response; negative regulation of DNA binding

Research Articles on CTNNBIP1

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Product Notes

The CTNNBIP1 ctnnbip1 (Catalog #AAA9629233) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CTNNBIP1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CTNNBIP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the CTNNBIP1 ctnnbip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTNNBIP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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