Western Blot (WB)
(Western Blot: Sample: Mouse Eye Tissue.)
Rabbit anti-Mouse Crystallin Beta B2 (CRYbB2) Polyclonal Antibody | anti-CRYbB2 antibody
Polyclonal Antibody to Crystallin Beta B2 (CRYbB2)
Immunohistochemistry: 5-20 ug/mL;1:25-100
Immunocytochemistry: 5-20 ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Store at 4°C for frequent use.
Aliquot and store at -20°C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Mouse Eye Tissue.)
Western Blot (WB)
(Western Blot: Sample: Mouse Eye Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant CRYbB2, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant CRYbB2, Mouse.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the beta-crystallin family. Beta crystallins, along with alpha and gamma crystallins, are the major proteins found in the eye lens. These proteins maintain the refractive index of the lens whilst also maintaining its transparency. Since lens central fiber cells lose their nuclei during development, crystallins are made and then retained throughout life, making them extremely stable proteins. Beta and gamma crystallins are considered be a superfamily and have a similar domain architecture, including four Greek Key motifs. Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. The protein encoded by this gene may have Ca2+-binding activity and could be associated with potential functions in the hippocampus and in sperm. Targeted knockout of this gene in mouse induces age-related cataract. A chain-terminating mutation in a similar gene in human was found to cause type 2 cerulean cataracts. [provided by RefSeq, Feb 2015]
Uniprot Description
CRYBB2: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Defects are the cause of congenital cerulean type 2 cataract, sutural cataract with punctate and cerulean opacities, and Coppock-like cataract.
Chromosomal Location of Human Ortholog: 5 F|5 55.38 cM
Molecular Function: identical protein binding; protein homodimerization activity; structural constituent of eye lens
Biological Process: camera-type eye development; visual perception
Research Articles on CRYbB2
Similar Products
Product Notes
The CRYbB2 crybb2 (Catalog #AAA2006023) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Crystallin Beta B2 (CRYbB2) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Crystallin Beta B2 (CRYbB2) can be used in a range of immunoassay formats including, but not limited to, Western blotting (WB); Immunocytochemistry (ICC); Immunohistochemistry (IHC); Immunoprecipitation (IP). Western blotting: 0.5-2 ug/mL;1:250-1000 Immunohistochemistry: 5-20 ug/mL;1:25-100 Immunocytochemistry: 5-20 ug/mL;1:25-100 Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the CRYbB2 crybb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Crystallin Beta B2 (CRYbB2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
