Goat anti-Dog CRP Polyclonal Antibody | anti-CRP antibody

Goat anti-Dog CRP - Antiserum

Cat. Num. AAA560221

• Gene Names: CRP; PTX1; MGC88244; MGC149895
• Reactivity: Dog
• Applications: ELISA
• Synonyms: CRP; Polyclonal Antibody; Goat anti-Dog CRP - Antiserum; Goat anti-Dog CRP (C- Reactive Protein); anti-Dog CRP; anti-CRP antibody

• Host: Goat
• Reactivity: Dog
• Clonality: Polyclonal
• Specificity: Monospecific by IEP versus normal dog serum.
• Form/Format: Liquid; Neat, Tris Buffered Saline

• Applicable Applications for anti-CRP antibody: ELISA
• Application Notes: ELISA: Assay Dependent; Optimal working dilutions should be determined experimentally by the investigator.
• Preservative: 0.09% sodium azide
• Antibody Type: Primary Antibody
• Specificity/Target: CRP
• Procedure: Goats were immunized with highly purified dog c-reactive protein (CRP) and the resulting antiserum was collected. The antiserum was delipidated , solid phase absorbed 0.45 um filtered. Total protein mesurement was determined by refractometer. Specific antibody content is determined immunoaffinity purification off an antigen containing immunoabsorbent.
• Immunogen: Dog CRP
• Specificity Note: This antiserum reacts with dog CRP as determined by IEP and Ouchterlony techniques. This antiserum may cross react with CRP from other species. Optimal working dilutions should be determined experimentally by the investigator.
• Total Protein: 30 mg/mL, as mesured by refractometer.
• Preparation and Storage: Store at 2-8°C.

Testing Data (TD)

(ELISA Raw Data)

Testing Data

Product Categories/Family for anti-CRP antibody

Dog Protein

NCBI and Uniprot Product Information

• NCBI GI #: 17975775
• NCBI GeneID: 1401
• UniProt Accession #: P02741; Q08AK3; Q8WW75; A8K078; D3DVD9; D3DVE0; Q5VVP7
• NCBI Official Full Name: CRP
• NCBI Official Synonym Full Names: C-reactive protein, pentraxin-related
• NCBI Official Symbol: CRP
• NCBI Official Synonym Symbols: PTX1; MGC88244; MGC149895
• NCBI Protein Information: C-reactive protein; pentraxin 1; OTTHUMP00000033307
• UniProt Protein Name: C-reactive protein
• Protein Family: Cryparin
• UniProt Gene Name: CRP
• UniProt Synonym Gene Names: PTX1
• UniProt Entry Name: CRP_HUMAN

NCBI Description

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq]

Uniprot Description

CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: extracellular space; growth cone; extracellular region; filopodium

Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; cholesterol binding; low-density lipoprotein binding; virion binding; calcium ion binding

Biological Process: protein polymerization; wound healing; defense response to Gram-positive bacterium; response to ethanol; negative regulation of vasodilation; positive regulation of superoxide release; response to lead ion; acute-phase response; response to hypoxia; opsonization; inflammatory response; complement activation, classical pathway; aging