Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human heart tissue slide using MBS768214 (CRLS1 Antibody) at dilution of 1:200)
Rabbit anti-Human, Mouse CRLS1 Polyclonal Antibody | anti-CRLS1 antibody
CRLS1 Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human heart tissue slide using MBS768214 (CRLS1 Antibody) at dilution of 1:200)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human heart tissue slide using MBS768214 (CRLS1 Antibody) at dilution of 1:200)
Western Blot (WB)
(mouse heart tissue were subjected to SDS PAGE followed by western blot with MBS768214 (CRLS1 antibody) at dilution of 1:300)
Western Blot (WB)
(mouse heart tissue were subjected to SDS PAGE followed by western blot with MBS768214 (CRLS1 antibody) at dilution of 1:300)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the CDP-alcohol phosphatidyltransferase class-I family of proteins. The encoded enzyme catalyzes the synthesis of cardiolipin, a phospholipid component of mitochondrial membranes that is critical for mitochondrial function. [provided by RefSeq, Apr 2016]
Uniprot Description
CRLS1: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Belongs to the CDP-alcohol phosphatidyltransferase class-I family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Lipid Metabolism - glycerophospholipid; EC 2.7.8.-; Mitochondrial; Transferase; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 20p13-p12.3
Cellular Component: integral to membrane; mitochondrial inner membrane; mitochondrion
Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; 2-acylglycerol-3-phosphate O-acyltransferase activity; cardiolipin synthase activity; CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity
Biological Process: cardiolipin biosynthetic process
Research Articles on CRLS1
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Product Notes
The CRLS1 crls1 (Catalog #AAA768214) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CRLS1 Rabbit Polyclonal reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CRLS1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CRLS1 crls1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRLS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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