Western Blot (WB)
(Western blot analysis of Phospho-CrkL (Tyr251) in lysates of COS7, using Phospho-CrkL (Tyr251) Antibody(13154).)
Rabbit CrkL Polyclonal Antibody | anti-CrkL antibody
CrkL (Phospho-Tyr251) Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Synonyms
CrkL; Polyclonal Antibody; CrkL (Phospho-Tyr251) Antibody; Crk L; Crk like protein; Crk-like protein; Crkl; CRKL_HUMAN; Crkol; HGNC:2363; Oncogene CrkL; V crk avian sarcoma virus CT10 oncogene homolog like; v crk sarcoma virus CT10 oncogene homolog (avian) like; V crk sarcoma virus CT10 oncogene homolog avian like;; anti-CrkL antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Phospho-CrkL (Phospho-Tyr251) Antibody detects endogenous levels of CrkL only when phosphorylated at Tyr251
Purity/Purification
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (varies by lot)
Sequence Length
303
Applicable Applications for anti-CrkL antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human CrkL around the phosphorylation site of Tyr251
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
Western Blot (WB)
(Western blot analysis of Phospho-CrkL (Tyr251) in lysates of COS7, using Phospho-CrkL (Tyr251) Antibody(13154).)
Western Blot (WB)
(Western blot analysis of Phospho-CrkL (Tyr251) in lysates of COS7, using Phospho-CrkL (Tyr251) Antibody(13154).)
Product Categories/Family for anti-CrkL antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39
NCBI Official Full Name
crk-like protein
NCBI Official Synonym Full Names
CRK like proto-oncogene, adaptor protein
NCBI Official Symbol
CRKL
NCBI Protein Information
crk-like protein
UniProt Protein Name
Crk-like protein
Protein Family
UniProt Gene Name
CRKL
NCBI Description
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]
Uniprot Description
May mediate the transduction of intracellular signals.
Research Articles on CrkL
Similar Products
Product Notes
The CrkL crkl (Catalog #AAA9429306) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CrkL (Phospho-Tyr251) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CrkL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the CrkL crkl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CrkL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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