Rabbit anti-Human CRISP-3 Polyclonal Antibody | anti-CRISP3 antibody

CRISP-3 (Cysteine-rich Secretory Protein 3, Specific Granule Protein of 28kD, SGP28, CRISP3)

Cat. Num. AAA647233

• Gene Names: CRISP3; Aeg2; CRS3; SGP28; CRISP-3; dJ442L6.3
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: CRISP-3; Polyclonal Antibody; CRISP-3 (Cysteine-rich Secretory Protein 3; Specific Granule Protein of 28kD; SGP28; CRISP3); Anti -CRISP-3 (Cysteine-rich Secretory Protein 3; anti-CRISP3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes both the N-glycosylated and non-glycosylated form of mature human CRISP-3.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.

• Applicable Applications for anti-CRISP3 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunohistochemistry.; Dilution: Western Blot: 1:10; Immunohistochemistry: Paraffin
• Immunogen: Recombinant corresponding to C-terminally truncated form of CRISP-3.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Related Product Information for anti-CRISP3 antibody

Cysteine-rich secretory protein 3 (CRISP-3; also known as SGP28) is a glycoprotein that belongs to the family of cysteine-rich secretory proteins (CRISPs) which was originally discovered in human neutrophilic granulocytes. CRISP-3 is also widely distibuted in exocrine glands (salivary glands, pancreas and prostate), eosinophilic granulocytes and to a lower level in epididymis, ovary, thymus and colon. The presence of CRISP-3 in neutrophils, eosinophils and in exocrine secretions indicates a role in innate host defense.

Product Categories/Family for anti-CRISP3 antibody

Antibodies; Abs to Cancer Markers

NCBI and Uniprot Product Information

• NCBI GI #: 300244562
• NCBI GeneID: 10321
• NCBI Accession #: NP_001177915.1
• NCBI GenBank Nucleotide #: NM_001190986.1
• UniProt Accession #: P54108; Q15512; Q3MJ82; Q53FA9; Q5JW83; Q9H108; A8K9S1; B2R8I8
• Molecular Weight: 27,630 Da
• NCBI Official Full Name: cysteine-rich secretory protein 3 isoform 2
• NCBI Official Synonym Full Names: cysteine-rich secretory protein 3
• NCBI Official Symbol: CRISP3
• NCBI Official Synonym Symbols: Aeg2; CRS3; SGP28; CRISP-3; dJ442L6.3
• NCBI Protein Information: cysteine-rich secretory protein 3; cysteine-rich secretory protein-3; specific granule protein (28 kDa); specific granule protein of 28 kDa
• UniProt Protein Name: Cysteine-rich secretory protein 3
• Protein Family: Cysteine-rich secretory protein
• UniProt Gene Name: CRISP3
• UniProt Synonym Gene Names: CRISP-3; SGP28
• UniProt Entry Name: CRIS3_HUMAN

Uniprot Description

Subunit structure: Interacts with A1BG. Ref.7

Subcellular location: Secreted. Note: In neutrophils, localized in specific granules.

Tissue specificity: Salivary gland, pancreas and prostate > epididymis, ovary, thymus and colon.

Sequence similarities: Belongs to the CRISP family.Contains 1 SCP domain.Contains 1 ShKT domain.

Sequence caution: The sequence AAH69580.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAH69602.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence BAG36185.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence CAA63984.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence CAA64527.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.