Rabbit anti-Human CRELD2 Polyclonal Antibody | anti-CRELD2 antibody

CRELD2, NT (CRELD2, Cysteine-rich with EGF-like domain protein 2) (APC)

Cat. Num. AAA6288737

• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CRELD2; Polyclonal Antibody; NT (CRELD2; Cysteine-rich with EGF-like domain protein 2) (APC); Cysteine-rich with EGF-like domain protein 2; anti-CRELD2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human CRELD2.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-CRELD2 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 23-51 in the N-terminal region of human CRELD2, UniProt Accession #NP_077300.3; Q6UXH1; Q2KIT5. Species sequence homology: bovine
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in Jurkat cell line lysates (35ug/lane) usingMBS6010000. This demonstrates that MBS6010000 detected the CRELD2 protein (arrow).)

Related Product Information for anti-CRELD2 antibody

CRELD2 may regulate transport of alpha4-beta2 neuronal acetylcholine receptor.

Product Categories/Family for anti-CRELD2 antibody

Antibodies; Amino Acids

References

1. Maslen, C.L., et al. Gene 382, 111-120 (2006). 2. Ortiz, J.A., et al. J. Neurochem. 95(6):1585-1596(2005). 3. Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004). 4. Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003). 5. Rupp, P.A., et al. Gene 293 (1-2), 47-57 (2002).

NCBI and Uniprot Product Information

• NCBI GI #: 205360958
• NCBI GeneID: 79174
• NCBI Accession #: NP_077300.3
• NCBI GenBank Nucleotide #: NM_024324.4
• UniProt Accession #: Q6UXH1; Q2KIT5
• Molecular Weight: 40,491 Da
• NCBI Official Full Name: cysteine-rich with EGF-like domain protein 2 isoform b
• NCBI Official Synonym Full Names: cysteine-rich with EGF-like domains 2
• NCBI Official Symbol: CRELD2
• NCBI Protein Information: cysteine-rich with EGF-like domain protein 2
• UniProt Protein Name: Cysteine-rich with EGF-like domain protein 2
• Protein Family: Cysteine-rich with EGF-like domain protein
• UniProt Gene Name: CRELD2
• UniProt Synonym Gene Names: UNQ185/PRO211
• UniProt Entry Name: CREL2_HUMAN

Uniprot Description

CRELD2: May regulate transport of alpha4-beta2 neuronal acetylcholine receptor. Belongs to the CRELD family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 22q13.33

Cellular Component: Golgi apparatus; extracellular space; endoplasmic reticulum

Molecular Function: protein binding; calcium ion binding