Rabbit anti-Human CREB3L4 Polyclonal Antibody | anti-CREB3L4 antibody

CREB3L4, CT (CREB3L4, AIBZIP, CREB4, JAL, Cyclic AMP-responsive element-binding protein 3-like protein 4, Androgen-induced basic leucine zipper protein, Attaching to CRE-like 1, Cyclic AMP-responsive element-binding protein 4, Transcript induced in spermi

Cat. Num. AAA6288653

• Gene Names: CREB3L4; JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CREB3L4; Polyclonal Antibody; CT (CREB3L4; AIBZIP; CREB4; JAL; Cyclic AMP-responsive element-binding protein 3-like protein 4; Androgen-induced basic leucine zipper protein; Attaching to CRE-like 1; Cyclic AMP-responsive element-binding protein 4; Transcript induced in spermi; Transcript induced in spermiogenesis protein 40; hJAL; Processed cyclic AMP-responsive element-binding protein 3-like protein 4; anti-CREB3L4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

• Applicable Applications for anti-CREB3L4 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CREB3L4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the C-terminal region of human CREB3L4.
• Conjugate: MaxLight405
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Related Product Information for anti-CREB3L4 antibody

cAMP response element-binding (CREB) proteins are a family of mammalian transcription activators. For further background information on CREB proteins, see CREB1 (MIM 123810).[supplied by OMIM].

Product Categories/Family for anti-CREB3L4 antibody

Antibodies; Binding Proteins

References

Ben Aicha, S., et al. Physiol. Genomics 31(2):295-305(2007). Stirling, J., et al. Mol. Biol. Cell 17(1):413-426(2006). Stelzer, G., et al. Endocrinology 143(5):1578-1588(2002). Qi, H., et al. Cancer Res. 62(3):721-733(2002). Cao, G., et al. J. Hum. Genet. 47(7):373-376(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 18702325
• NCBI GeneID: 148327
• NCBI Accession #: NP_570968.1
• NCBI GenBank Nucleotide #: NM_130898.3
• UniProt Accession #: Q8TEY5; Q5T4L0; Q86YW6; D3DV62
• Molecular Weight: 41,275 Da
• NCBI Official Full Name: cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 1
• NCBI Official Synonym Full Names: cAMP responsive element binding protein 3-like 4
• NCBI Official Symbol: CREB3L4
• NCBI Official Synonym Symbols: JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP
• NCBI Protein Information: cyclic AMP-responsive element-binding protein 3-like protein 4; CREB-4; tisp40; attaching to CRE-like 1; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 4; androgen-induced basic leucine zipper protein; cyclic AMP-respon
• UniProt Protein Name: Cyclic AMP-responsive element-binding protein 3-like protein 4
• Protein Family: Cyclic AMP-responsive element-binding protein 3-like protein
• UniProt Gene Name: CREB3L4
• UniProt Synonym Gene Names: AIBZIP; CREB4; JAL; cAMP-responsive element-binding protein 3-like protein 4; AIbZIP; ATCE1; CREB-4; cAMP-responsive element-binding protein 4; Tisp40
• UniProt Entry Name: CR3L4_HUMAN

NCBI Description

This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Uniprot Description

CREB3L4: Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements. Belongs to the bZIP family. ATF subfamily.

Protein type: Transcription factor; Membrane protein, integral; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane; nucleus

Biological Process: transcription, DNA-dependent; unfolded protein response; positive regulation of transcription from RNA polymerase II promoter; spermatogenesis