Rabbit anti-Human CREB3L4 Polyclonal Antibody | anti-CREB3L4 antibody

CREB3L4, CT (CREB3L4, AIBZIP, CREB4, JAL, Cyclic AMP-responsive element-binding protein 3-like protein 4, Androgen-induced basic leucine zipper protein, Attaching to CRE-like 1, Cyclic AMP-responsive element-binding protein 4, Transcript induced in spermi

Cat. Num. AAA6288648

• Gene Names: CREB3L4; JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: CREB3L4; Polyclonal Antibody; CT (CREB3L4; AIBZIP; CREB4; JAL; Cyclic AMP-responsive element-binding protein 3-like protein 4; Androgen-induced basic leucine zipper protein; Attaching to CRE-like 1; Cyclic AMP-responsive element-binding protein 4; Transcript induced in spermi; Transcript induced in spermiogenesis protein 40; hJAL; Processed cyclic AMP-responsive element-binding protein 3-like protein 4; anti-CREB3L4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-CREB3L4 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: CREB3L4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the C-terminal region of human CREB3L4.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(CREB3L4 Antibody (C-term) western blot analysis in PC-3 cell line lysates (35ug/lane).This demonstrates the CREB3L4 antibody detected the CREB3L4 protein (arrow).)

Related Product Information for anti-CREB3L4 antibody

cAMP response element-binding (CREB) proteins are a family of mammalian transcription activators. For further background information on CREB proteins, see CREB1 (MIM 123810).[supplied by OMIM].

Product Categories/Family for anti-CREB3L4 antibody

Antibodies; Binding Proteins

References

Ben Aicha, S., et al. Physiol. Genomics 31(2):295-305(2007). Stirling, J., et al. Mol. Biol. Cell 17(1):413-426(2006). Stelzer, G., et al. Endocrinology 143(5):1578-1588(2002). Qi, H., et al. Cancer Res. 62(3):721-733(2002). Cao, G., et al. J. Hum. Genet. 47(7):373-376(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 18702325
• NCBI GeneID: 148327
• NCBI Accession #: NP_570968.1
• NCBI GenBank Nucleotide #: NM_130898.3
• UniProt Accession #: Q8TEY5; Q5T4L0; Q86YW6; D3DV62
• Molecular Weight: 41,275 Da
• NCBI Official Full Name: cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 1
• NCBI Official Synonym Full Names: cAMP responsive element binding protein 3-like 4
• NCBI Official Symbol: CREB3L4
• NCBI Official Synonym Symbols: JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP
• NCBI Protein Information: cyclic AMP-responsive element-binding protein 3-like protein 4; CREB-4; tisp40; attaching to CRE-like 1; cAMP responsive element binding protein 1; cAMP-responsive element-binding protein 4; androgen-induced basic leucine zipper protein; cyclic AMP-respon
• UniProt Protein Name: Cyclic AMP-responsive element-binding protein 3-like protein 4
• Protein Family: Cyclic AMP-responsive element-binding protein 3-like protein
• UniProt Gene Name: CREB3L4
• UniProt Synonym Gene Names: AIBZIP; CREB4; JAL; cAMP-responsive element-binding protein 3-like protein 4; AIbZIP; ATCE1; CREB-4; cAMP-responsive element-binding protein 4; Tisp40
• UniProt Entry Name: CR3L4_HUMAN

NCBI Description

This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Uniprot Description

CREB3L4: Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements. Belongs to the bZIP family. ATF subfamily.

Protein type: Transcription factor; Membrane protein, integral; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane; nucleus

Biological Process: transcription, DNA-dependent; unfolded protein response; positive regulation of transcription from RNA polymerase II promoter; spermatogenesis