Rabbit anti-Human CRABP2 Polyclonal Antibody | anti-CRABP2 antibody

CRABP2 Antibody

Cat. Num. AAA9400722

• Gene Names: CRABP2; RBP6; CRABP-II
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen affinity purification.
• Synonyms: CRABP2; Polyclonal Antibody; CRABP2 Antibody; RBP6; CRABP-II; anti-CRABP2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total CRABP2 protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
• Concentration: 2 mg/ml (varies by lot)
• Sequence Length: 138

• Applicable Applications for anti-CRABP2 antibody: Immunohistochemistry (IHC)
• Application Notes: Immunohistochemistry: 1:50-1:200
• Immunogen Type: Recombinant Protein
• Immunogen Description: Full length fusion protein
• Target Name: CRABP2
• Preparation and Storage: Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/40.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/40.)

Related Product Information for anti-CRABP2 antibody

This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Product Categories/Family for anti-CRABP2 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 315013542
• NCBI GeneID: 1382
• NCBI Accession #: NP_001186652.1
• NCBI GenBank Nucleotide #: NM_001199723.1
• UniProt Accession #: P29373; Q6ICN6; B2R4Z8; D3DVC5; F1T098
• Molecular Weight: 15,693 Da
• NCBI Official Full Name: cellular retinoic acid-binding protein 2
• NCBI Official Synonym Full Names: cellular retinoic acid binding protein 2
• NCBI Official Symbol: CRABP2
• NCBI Official Synonym Symbols: RBP6; CRABP-II
• NCBI Protein Information: cellular retinoic acid-binding protein 2
• UniProt Protein Name: Cellular retinoic acid-binding protein 2
• Protein Family: Cellular retinoic acid-binding protein
• UniProt Gene Name: CRABP2
• UniProt Synonym Gene Names: CRABP-II
• UniProt Entry Name: RABP2_HUMAN

NCBI Description

This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2010]

Uniprot Description

CRABP2: Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: nucleoplasm; endoplasmic reticulum; cytoplasm; cytosol

Molecular Function: retinoid binding; retinoic acid binding; transporter activity; retinal binding; retinol binding

Biological Process: embryonic forelimb morphogenesis; epidermis development; regulation of transcription, DNA-dependent; retinoic acid metabolic process; signal transduction; transmembrane transport