Western Blot (WB)
(CRABP1 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the CRABP1 antibody detected the CRABP1 protein (arrow).)
Rabbit CRABP1 Polyclonal Antibody | anti-CRABP1 antibody
CRABP1 Antibody (C-term)
Western Blot (WB)
(CRABP1 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the CRABP1 antibody detected the CRABP1 protein (arrow).)
Western Blot (WB)
(CRABP1 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the CRABP1 antibody detected the CRABP1 protein (arrow).)
Immunohistochemistry (IHC)
(CRABP1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CRABP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(CRABP1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CRABP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
A family member and is thought to play an important role in
retinoic acid-mediated differentiation and proliferation processes.
It is structurally similar to the cellular retinol-binding
proteins, but binds only retinoic acid at specific sites within the
nucleus, which may contribute to vitamin A-directed differentiation
in epithelial tissue.
Uhrig, M., et al. BMC Med 6, 38 (2008) :
Guidez, F., et al. Proc. Natl. Acad. Sci. U.S.A. 104(47):18694-18699(2007)
Tanaka, K., et al. Oncogene 26(44):6456-6468(2007)
Wu, Q., et al. Mol. Cancer 6, 45 (2007) :
Flagiello, D., et al. Cytogenet. Cell Genet. 76 (1-2), 17-18 (1997) :
Liu, W., et al. Biochem. Biophys. Res. Commun. 229(3):922-929(1996)
Eller, M.S., et al. Exp. Cell Res. 198(2):328-336(1992)
Astrom, A., et al. J. Biol. Chem. 266(26):17662-17666(1991)
Ong, D.E. Arch Dermatol 123 (12), 1693-1695A (1987) :
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. [provided by RefSeq, Jul 2008]
Uniprot Description
CRABP1: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Chromosomal Location of Human Ortholog: 15q24
Cellular Component: cytosol
Molecular Function: protein binding; retinoid binding; retinoic acid binding; transporter activity; retinol binding; retinal binding
Biological Process: transport; multicellular organismal development; signal transduction
Research Articles on CRABP1
Similar Products
Product Notes
The CRABP1 crabp1 (Catalog #AAA9210771) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 90-118. The CRABP1 Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Bovine, Chicken, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's CRABP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the CRABP1 crabp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRABP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
