Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver cancer using MBS768174 (CPT1A antibody) at dilution of 1:100)
Rabbit CPT1A Polyclonal Antibody | anti-CPT1A antibody
CPT1A Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver cancer using MBS768174 (CPT1A antibody) at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver cancer using MBS768174 (CPT1A antibody) at dilution of 1:100)
Testing Data
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Testing Data
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Western Blot (WB)
(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS768174 (CPT1A antibody) at dilution of 1:1000)
Western Blot (WB)
(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS768174 (CPT1A antibody) at dilution of 1:1000)
NCBI and Uniprot Product Information
NCBI Description
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
CPT1A: Belongs to the carnitine/choline acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Transferase; EC 2.3.1.21; Membrane protein, integral; Mitochondrial; Lipid Metabolism - fatty acid
Chromosomal Location of Human Ortholog: 11q13.2
Cellular Component: integral to mitochondrial outer membrane; membrane; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion
Molecular Function: carnitine O-palmitoyltransferase activity; identical protein binding
Biological Process: carnitine metabolic process; carnitine shuttle; circadian rhythm; eating behavior; epithelial cell differentiation; fatty acid beta-oxidation; glucose metabolic process; long-chain fatty acid metabolic process; positive regulation of fatty acid beta-oxidation; protein homooligomerization; regulation of insulin secretion; response to drug; response to organic cyclic substance; triacylglycerol metabolic process
Disease: Carnitine Palmitoyltransferase I Deficiency
Research Articles on CPT1A
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Product Notes
The CPT1A cpt1a (Catalog #AAA768174) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CPT1A Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CPT1A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). Researchers should empirically determine the suitability of the CPT1A cpt1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CPT1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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