Western Blot (WB)
(CPSF6 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CPSF6 antibody detected the CPSF6 protein (arrow).)
Rabbit anti-Human CPSF6 Polyclonal Antibody | anti-CPSF6 antibody
CPSF6, NT (CPSF6, CFIM68, Cleavage and polyadenylation specificity factor subunit 6, Cleavage and polyadenylation specificity factor 68kD subunit, Pre-mRNA cleavage factor Im 68kD subunit, Protein HPBRII-4/7)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(CPSF6 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CPSF6 antibody detected the CPSF6 protein (arrow).)
Western Blot (WB)
(CPSF6 Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CPSF6 antibody detected the CPSF6 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]
Uniprot Description
CPSF6: Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping. Belongs to the RRM CPSF6/7 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA processing; Spliceosome; RNA-binding
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: nucleoplasm; membrane; ribonucleoprotein complex; paraspeckles; nucleus; mRNA cleavage factor complex
Molecular Function: mRNA binding; protein binding; RNA binding; nucleotide binding
Biological Process: mRNA polyadenylation; mRNA processing; protein tetramerization
Research Articles on CPSF6
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Product Notes
The CPSF6 cpsf6 (Catalog #AAA6000103) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CPSF6, NT (CPSF6, CFIM68, Cleavage and polyadenylation specificity factor subunit 6, Cleavage and polyadenylation specificity factor 68kD subunit, Pre-mRNA cleavage factor Im 68kD subunit, Protein HPBRII-4/7) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CPSF6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the CPSF6 cpsf6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CPSF6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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