Western Blot (WB)
(Western blot analysis of lysate from human brain tissue lysate, using CPLX3 Antibody (Center). MBS9213995 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Rabbit CPLX3 Polyclonal Antibody | anti-CPLX3 antibody
CPLX3 Antibody (Center)
Gene Names
CPLX3; CPXIII; CPX-III; Nbla11589
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CPLX3; Polyclonal Antibody; CPLX3 Antibody (Center); Complexin-3; Complexin III; CPX III; anti-CPLX3 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CPLX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the Central region of human CPLX3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
52-81
Sequence Length
158
Applicable Applications for anti-CPLX3 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(Western blot analysis of lysate from human brain tissue lysate, using CPLX3 Antibody (Center). MBS9213995 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Western Blot (WB)
(Western blot analysis of lysate from human brain tissue lysate, using CPLX3 Antibody (Center). MBS9213995 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Immunohistochemistry (IHC)
(CPLX3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CPLX3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(CPLX3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CPLX3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-CPLX3 antibody
Positively regulates a late step in synaptic vesicle exocytosis (By similarity).
References
Newton-Cheh, C., et al. Nat. Genet. (2009) In press :
Levy, D., et al. Nat. Genet. (2009) In press :
Reim, K., et al. J. Cell Biol. 169(4):669-680(2005)
Ohira, M., et al. Oncogene 22(35):5525-5536(2003)
Levy, D., et al. Nat. Genet. (2009) In press :
Reim, K., et al. J. Cell Biol. 169(4):669-680(2005)
Ohira, M., et al. Oncogene 22(35):5525-5536(2003)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17557
NCBI Official Full Name
complexin-3
NCBI Official Synonym Full Names
complexin 3
NCBI Official Symbol
CPLX3
NCBI Official Synonym Symbols
CPXIII; CPX-III; Nbla11589
NCBI Protein Information
complexin-3
UniProt Protein Name
Complexin-3
Protein Family
UniProt Gene Name
CPLX3
UniProt Synonym Gene Names
CPX III
UniProt Entry Name
CPLX3_HUMAN
Uniprot Description
CPLX3: Positively regulates a late step in synaptic vesicle exocytosis. Belongs to the complexin/synaphin family.
Chromosomal Location of Human Ortholog: 15q24.1
Cellular Component: plasma membrane; synapse; cytosol; cell junction
Molecular Function: syntaxin binding; neurotransmitter transporter activity
Biological Process: synaptic vesicle exocytosis; insulin secretion; regulation of neurotransmitter secretion
Research Articles on CPLX3
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Product Notes
The CPLX3 cplx3 (Catalog #AAA9213995) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 52-81. The CPLX3 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's CPLX3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). WB~~1:1000. Researchers should empirically determine the suitability of the CPLX3 cplx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CPLX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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