Western Blot (WB)
(Staining (0.5ug/ml) of human brain lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)
Goat CPEB1 Polyclonal Antibody | anti-CPEB1 antibody
Goat anti-CPEB1 Antibody
Western Blot: Approx 65-70kDa band observed in human brain lysates (predicted MW of 65kDa according to NP_085097). Recommended for use at 0.5-2ug/ml. Please note this band was always accompanied by a slightly stonger band at approx 48kDa and further both bands could be blocked by incubation with the immunising peptide.
Western Blot (WB)
(Staining (0.5ug/ml) of human brain lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)
Western Blot (WB)
(Staining (0.5ug/ml) of human brain lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Uniprot Description
CPEB: cytoplasmic polyadenylation element binding protein 1. Binds to the protein CPE and drives its polyadenylation. Activated by the protein kinase AurA. Insulin and progesterone stimulate AurA-catalyzed phosphorylation of CPEB in oocytes. Neuronal CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia.
Protein type: Translation; RNA-binding
Chromosomal Location of Human Ortholog: 15q25.2
Cellular Component: cell junction; cell soma; centrosome; cytoplasm; dendrite; growth cone; neuron projection; nucleoplasm; nucleus; perinuclear region of cytoplasm; postsynaptic density; postsynaptic membrane; synapse
Molecular Function: metal ion binding; mRNA 3'-UTR binding; nucleotide binding; ribosome binding; translation factor activity, nucleic acid binding; translation repressor activity, nucleic acid binding
Biological Process: cellular response to insulin stimulus; mRNA processing; mRNA transport; negative regulation of cell proliferation; positive regulation of cell migration; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of translation; translation
Research Articles on CPEB1
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Product Notes
The CPEB1 cpeb1 (Catalog #AAA420722) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-CPEB1 Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's CPEB1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 65-70kDa band observed in human brain lysates (predicted MW of 65kDa according to NP_085097). Recommended for use at 0.5-2ug/ml. Please note this band was always accompanied by a slightly stonger band at approx 48kDa and further both bands could be blocked by incubation with the immunising peptide. Researchers should empirically determine the suitability of the CPEB1 cpeb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: PLMRNQKNRD SS. It is sometimes possible for the material contained within the vial of "CPEB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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