Flow Cytometry (FC/FACS)
(Wistar rat splenocytes (left) or lymph nodes (right) were stained with anti-CD4 (clone: W3/25)(filled histogram) or mouse IgG1 isotype control (open histogram).)
Rabbit anti-SARS-CoV-2 COVID 19 Spike RBD Coronavirus Polyclonal Antibody | anti-COVID-19 antibody
Anti-SARS-CoV-2 Spike RBD, HRPO (Polyclonal)(Rabbit IgG)
Reactivity
SARS-CoV-2
Applications
ELISA
Synonyms
COVID 19 Spike RBD Coronavirus; Polyclonal Antibody; Anti-SARS-CoV-2 Spike RBD; HRPO (Polyclonal)(Rabbit IgG); 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Spike RBD; anti-COVID-19 antibody
Host
Rabbit
Reactivity
SARS-CoV-2
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
2019-nCoV Spike protein S1 subunit, receptor-binding domain (RBD)(aa319-541)
Form/Format
HRPO conjugated IgG buffered in PBS with 40% glycerol (v/v) and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5mg/ml. No NaN3 with other preservatives.
Applicable Applications for anti-COVID-19 antibody
ELISA (EIA)
Application Notes
ELISA: 1:16K-1:32K
Conjugation
Horseradish Peroxidase (HRPO)
Immunogen
Recombinant 2019-nCoV Spike protein S1 subunit, receptor-binding domain (RBD)(aa319-541) expressed in CHO cells.
Preparation and Storage
Store at 4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles.
Flow Cytometry (FC/FACS)
(Wistar rat splenocytes (left) or lymph nodes (right) were stained with anti-CD4 (clone: W3/25)(filled histogram) or mouse IgG1 isotype control (open histogram).)
Flow Cytometry (FC/FACS)
(Wistar rat splenocytes (left) or lymph nodes (right) were stained with anti-CD4 (clone: W3/25)(filled histogram) or mouse IgG1 isotype control (open histogram).)
Related Product Information for anti-COVID-19 antibody
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)is the strain of coronavirus that causes coronavirus disease 2019 (COVID-19), the respiratory illness responsible for the COVID-19 pandemic. Like other coronaviruses, SARS-CoV-2 is comprised of four structural proteins: spike (S), envelope (E), membrane (M), andnucleocapsid(N) proteins.The spike (S) protein is a type I transmembrane glycoprotein that is comprised of two subunits, S1 and S2. Within the S1 subunit is a receptor binding domain (RBD), that is responsible for binding to the receptor angiotensin converting enzyme 2 (ACE2)and allowing the virus to enter host cells. As the RBD is responsiblefor initial viral entry into the host cell,it has become anattractive target for therapeutics and vaccines.
References
1. Gorbalenya AE, et al. (2020). The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nature Microbiology. 5 (4): 536-544.
2. Wu C, et al. (2020). Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods. Acta Pharmaceutica Sinica B. 10 (5): 766-788.
3. Xiao X, et al. (2004) The SARS-CoV S glycoprotein. Cell Mol Life Sci. 61(19-20):2428-2430.
4. Lan J, et al. Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor. Nature. 2020;581(7807):215-220.
2. Wu C, et al. (2020). Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods. Acta Pharmaceutica Sinica B. 10 (5): 766-788.
3. Xiao X, et al. (2004) The SARS-CoV S glycoprotein. Cell Mol Life Sci. 61(19-20):2428-2430.
4. Lan J, et al. Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor. Nature. 2020;581(7807):215-220.
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Product Notes
The COVID-19 (Catalog #AAA524576) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SARS-CoV-2 Spike RBD, HRPO (Polyclonal)(Rabbit IgG) reacts with SARS-CoV-2 and may cross-react with other species as described in the data sheet. AAA Biotech's COVID 19 Spike RBD Coronavirus can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:16K-1:32K. Researchers should empirically determine the suitability of the COVID-19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COVID 19 Spike RBD Coronavirus, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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