Western Blot/Blotting
(Western blot analysis of CRMP1 in 3T3 cell lysate with CRMP1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.)
Rabbit Collapsin response mediator protein 1 Polyclonal Antibody | anti-CRMP1 antibody
Collapsin response mediator protein 1 (CT)
Western Blot/Blotting
(Western blot analysis of CRMP1 in 3T3 cell lysate with CRMP1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.)
Western Blot/Blotting
(Western blot analysis of CRMP1 in 3T3 cell lysate with CRMP1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Ref.11
Subunit structure: Homotetramer, and heterotetramer with DPYSL2, DPYSL3, DPYSL4 or DPYSL5. Interacts with PLXNA1
By similarity. Ref.10
Subcellular location: Cytoplasm. Cytoplasm › cytoskeleton › centrosome. Cytoplasm › cytoskeleton › spindle. Note: Associated with centrosomes and the mitotic spindle during metaphase. Ref.11
Tissue specificity: Brain.
Sequence similarities: Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
Caution: Lacks most of the conserved residues that are essential for binding the metal cofactor and hence for dihydropyrimidinase activity. Its enzyme activity is therefore unsure.
Research Articles on CRMP1
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Product Notes
The CRMP1 crmp1 (Catalog #AAA395495) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Collapsin response mediator protein 1 (CT) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Collapsin response mediator protein 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the CRMP1 crmp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Collapsin response mediator protein 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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