Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46951(CHERP Antibody) at dilution 1/20. (Original magnification: 200))
Rabbit anti-Human COG2 Polyclonal Antibody | anti-COG2 antibody
COG2 Antibody
Gene Names
COG2; LDLC; CDG2Q
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
COG2; Polyclonal Antibody; COG2 Antibody; LDLC; anti-COG2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total COG2 protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
0.8mg/ml (varies by lot)
Sequence Length
2940
Applicable Applications for anti-COG2 antibody
Immunohistochemistry (IHC)
Application Notes
IF: 1: 25-100
Immunogen
Fusion protein of human COG2
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C.
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46951(CHERP Antibody) at dilution 1/20. (Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46951(CHERP Antibody) at dilution 1/20. (Original magnification: 200))
Related Product Information for anti-COG2 antibody
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-COG2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
83,136 Da
NCBI Official Full Name
Homo sapiens component of oligomeric golgi complex 2, mRNA
NCBI Official Synonym Full Names
component of oligomeric golgi complex 2
NCBI Official Symbol
COG2
NCBI Official Synonym Symbols
LDLC; CDG2Q
NCBI Protein Information
conserved oligomeric Golgi complex subunit 2
UniProt Protein Name
Conserved oligomeric Golgi complex subunit 2
Protein Family
UniProt Gene Name
COG2
UniProt Synonym Gene Names
LDLC; COG complex subunit 2
NCBI Description
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009]
Uniprot Description
Required for normal Golgi morphology and function.
Research Articles on COG2
1. Our data strongly suggest that these compound heterozygous mutations in COG2 are causative of CDG.
Similar Products
Product Notes
The COG2 cog2 (Catalog #AAA9429916) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The COG2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's COG2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IF: 1: 25-100. Researchers should empirically determine the suitability of the COG2 cog2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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