Immunohistochemistry (IHC)
(Anti-CNTF Picoband antibody, MBS176996-1.JPGIHC(P): Mouse Brain Tissue )
Rabbit anti-Mouse, Rat CNTF Polyclonal Antibody | anti-CNTF antibody
Anti-CNTF Antibody
Reactivity
Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Immunogen affinity purified.
Synonyms
CNTF; Polyclonal Antibody; Anti-CNTF Antibody; Ciliary neurotrophic factor; ciliary neurotrophic factor; Ciliary Neurotrophic Factor antibody; CNTF antibody; CNTF_HUMAN antibody; HCNTF antibody; anti-CNTF antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
200
Applicable Applications for anti-CNTF antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Immunogen
E Coli-derived rat CNTF recombinant protein (Position: A2-M200). Rat CNTF shares 84% and 95% amino acid (aa) sequences identity with human and mouse CNTF, respectively.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Immunohistochemistry (IHC)
(Anti-CNTF Picoband antibody, MBS176996-1.JPGIHC(P): Mouse Brain Tissue )
Immunohistochemistry (IHC)
(Anti-CNTF Picoband antibody, MBS176996-1.JPGIHC(P): Mouse Brain Tissue )
Immunohistochemistry (IHC)
(Anti-CNTF Picoband antibody, MBS176996-2.JPGIHC(P): Rat Brain Tissue )
Immunohistochemistry (IHC)
(Anti-CNTF Picoband antibody, MBS176996-2.JPGIHC(P): Rat Brain Tissue )
Testing Data
(Anti-CNTF Picoband antibody, MBS176996-3.jpgAll lanes: Anti-CNTF(MBS176996) at 0.5ug/mlLane 1: PC-12 Whole Cell Lysate at 40ugLane 2: NRK Whole Cell Lysate at 40ugLane 3: RH35 Whole Cell Lysate at 40ugLane 4: Rat Brain Tissue Lysate at 40ugLane 5: Rat Liver Tissue Lysate at 40ugLane 6: Rat Spleen Tissue Lysate at 40ugLane 7: Rat Testis Tissue Lysate at 40ugPredicted bind size: 23KDObserved bind size: 23KD)
Testing Data
(Anti-CNTF Picoband antibody, MBS176996-3.jpgAll lanes: Anti-CNTF(MBS176996) at 0.5ug/mlLane 1: PC-12 Whole Cell Lysate at 40ugLane 2: NRK Whole Cell Lysate at 40ugLane 3: RH35 Whole Cell Lysate at 40ugLane 4: Rat Brain Tissue Lysate at 40ugLane 5: Rat Liver Tissue Lysate at 40ugLane 6: Rat Spleen Tissue Lysate at 40ugLane 7: Rat Testis Tissue Lysate at 40ugPredicted bind size: 23KDObserved bind size: 23KD)
Related Product Information for anti-CNTF antibody
Description: Rabbit IgG polyclonal antibody for Ciliary neurotrophic factor(CNTF) detection. Tested with WB, IHC-P, ELISA in Mouse, Rat.
Background: Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone andnerve growth factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations includingastrocytes. It is mapped to 11q12.1. In addition to neurotrophic effects on parasympathetic neurons, CNTF was shown to have activities on sympathetic and sensory neurons. CNTF appears not to be involved in motor neuron survival during development. human CNTF has a trophic influence on degenerating striatal neurons as well as on critical nonstriatal regions. CNTF plays a role in a cardiac signal transduction pathway that regulates obesity-related left ventricular hypertrophy.
Background: Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone andnerve growth factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations includingastrocytes. It is mapped to 11q12.1. In addition to neurotrophic effects on parasympathetic neurons, CNTF was shown to have activities on sympathetic and sensory neurons. CNTF appears not to be involved in motor neuron survival during development. human CNTF has a trophic influence on degenerating striatal neurons as well as on critical nonstriatal regions. CNTF plays a role in a cardiac signal transduction pathway that regulates obesity-related left ventricular hypertrophy.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
22,854 Da
NCBI Official Full Name
Ciliary neurotrophic factor
NCBI Official Synonym Full Names
ciliary neurotrophic factor
NCBI Official Symbol
Cntf
NCBI Protein Information
ciliary neurotrophic factor; ciliary neurotropic factor
UniProt Protein Name
Ciliary neurotrophic factor
Protein Family
UniProt Gene Name
Cntf
UniProt Synonym Gene Names
CNTF
UniProt Entry Name
CNTF_RAT
NCBI Description
a cytokine involved in neuronal degeneration and adipocyte gene expression [RGD, Feb 2006]
Uniprot Description
CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Research Articles on CNTF
Similar Products
Product Notes
The CNTF cntf (Catalog #AAA176996) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CNTF Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CNTF can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA). Researchers should empirically determine the suitability of the CNTF cntf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNTF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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