Rabbit anti-Human, Mouse CMTR1 Polyclonal Antibody | anti-CMTR1 antibody
CMTR1 Antibody
Gene Names
CMTR1; MTr1; hMTr1; FTSJD2; KIAA0082
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
CMTR1; Polyclonal Antibody; CMTR1 Antibody; Cap methyltransferase 1; Cap-specific mRNA (nucleoside-2''-O-)-methyltransferase 1; Cap1 2''O-ribose methyltransferase 1; CMTR1_HUMAN; FLJ22156; FtsJ methyltransferase domain containing 2; FtsJ methyltransferase domain-containing protein 2; FTSJD 2; hMTr1; Interferon-stimulated gene 95 kDa protein; ISG95; KIAA0082; MTr1; OTTHUMP00000016324; Uncharacterized protein KIAA0082; anti-CMTR1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
CMTR1 Antibody detects endogenous levels of CMTR1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CMTR1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human CMTR1.
Conjugation
Unconjugated
Subunit Structure
Interacts with POLR2A (via C-terminus).
Function
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
95,321 Da
NCBI Official Full Name
cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
NCBI Official Synonym Full Names
cap methyltransferase 1
NCBI Official Symbol
CMTR1
NCBI Official Synonym Symbols
MTr1; hMTr1; FTSJD2; KIAA0082
NCBI Protein Information
cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
UniProt Protein Name
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
UniProt Gene Name
CMTR1
UniProt Synonym Gene Names
FTSJD2; KIAA0082; MTR1; MTr1; hMTr1; ISG95
Uniprot Description
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m7GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m7GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
Research Articles on CMTR1
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Product Notes
The CMTR1 cmtr1 (Catalog #AAA9630997) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CMTR1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CMTR1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the CMTR1 cmtr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CMTR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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